80 Results for "

Gag

" in MedChemExpress (MCE) Product Catalog:
Products (80)

80 Results for "Gag" in MCE Product Catalog:

7
Mitoguazone
Mitoguazone
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7 Publications Verification
Cat. No.: HY-106634
CAS No.: 459-86-9
Purity:  99.33%
Synonyms: Methylglyoxal-bis(guanylhydrazone); MGBG; Methyl-Gag
Target:  

HIV Apoptosis

Research Areas:  

Infection Cancer

Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment .
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5
Dextran sulfate sodium salt (MW 5000)
Dextran sulfate sodium salt (MW 5000)
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5 Cited Publications
Cat. No.: HY-116282
CAS No.: 9011-18-1
Purity:  99.20%
Synonyms: DSS (MW 5000); DXS (MW 5000)
Dextran sulfate sodium salt (DSS) (MW 5000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt (DSS) with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 5000) is an inhibitor of complement and coagulation pathways, and belongs to the glycosaminoglycans (GAG) family. Dextran sulfate sodium salt (MW 5000) acts as an anticoagulant, antiviral, and anti-lipemic agent. Dextran sulfate sodium salt (DSS) stops HIV-1 virus adsorption to host cells. Dextran sulfate sodium salt (MW 5000) prevents NK cell-mediated cytotoxicity. Dextran sulfate sodium salt (MW 5000) inhibits instant blood-mediated inflammatory reaction (IBMIR) .
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5
Fosamprenavir
Fosamprenavir
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5 Cited Publications
Cat. No.: HY-78726
CAS No.: 226700-79-4
Synonyms: Amprenavir phosphate; GW 433908
Target:  

Drug Intermediate HIV HIV Protease

Research Areas:  

Infection

Fosamprenavir is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir can be used for the study of human immunodeficiency virus (HIV-1) infection .
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5
Fosamprenavir Calcium Salt
Fosamprenavir Calcium Salt
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5 Cited Publications
Cat. No.: HY-17431
CAS No.: 226700-81-8
Synonyms: GW433908G
Target:  

Drug Intermediate HIV HIV Protease

Research Areas:  

Infection

Fosamprenavir Calcium Salt (GW433908G) is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir Calcium Salt is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir Calcium Salt can be used for the study of human immunodeficiency virus (HIV-1) infection .
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2
ODN 1018
ODN 1018
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2 Cited Publications
Cat. No.: HY-150724
CAS No.: 937402-51-2
Synonyms: 1018 ISS
Target:  

Toll-like Receptor (TLR)

Research Areas:  

Inflammation/Immunology

ODN 1018 (1018 ISS) is a TLR9 agonist and immune modulator. ODN 1018 exhibits adjuvant activity and augments CD8+ T cell responses with LNP-encapsulated OVA peptides. ODN 1018 triggers sustained suppression of allergic airway inflammation. ODN 1018 can be used for the research of allergic asthma and systemic lupus erythematosus .
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2
Chondroitinase ABC
Chondroitinase ABC
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2 Cited Publications
Cat. No.: HY-P2727
CAS No.: 9024-13-9
Synonyms: ChABC
Target:  

Biochemical Assay Reagents

Research Areas:  

Neurological Disease

Chondroitinase ABC (ChABC) is an enzyme that degrades glycosaminoglycan side-chains of chondroitin sulfate (CS-GAG) from the chondroitin sulfate proteoglycan (CSPG) core protein. Chondroitinase ABC facilitates reinnervation by degrading CS-GAGs around motoneurons. Chondroitinase ABC has the potential for the research of spinal injury .
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2
Bevirimat
Bevirimat
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2 Cited Publications
Cat. No.: HY-N0842
CAS No.: 174022-42-5
Synonyms: PA-457; MPC-4326; YK FH312
Category:  

Infection Triterpenes Terpenoids Plants Disease Research Fields 500 - Internal Server Error | MedChemExpress

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