country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

12 Results for "

Gingival

" in MedChemExpress (MCE) Product Catalog:

Products (12)

Sort by :

Categories

By Targets

Species:

Tags:

Sources:

Hosts:

Reactivities:

Applications:

Isotypes:

Conjugations:

Clonalities:

Modifications:

Products

Ercalcitriol

3 Cited Publications

Cat. No.: HY-32350

CAS No.: 60133-18-8

Synonyms: 1α,25-Dihydroxy Vitamin D2

Category:

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:

VD/VDR Drug Metabolite Endogenous Metabolite

Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is a vitamin D receptor (VDR) agonist with high binding affinity. After binding to VDR, Ercalcitriol forms a complex with retinoid X receptor (RXR) to regulate target gene transcription. For example, Ercalcitriol induces human gingival/oral epithelial cells to produce human cat antimicrobial peptide (hCAP-18/LL-37), which has antimicrobial activity against periodontal pathogens such as Porphyromonas gingivalis. Ercalcitriol enhances the innate immune defense of the oral mucosa by promoting the expression of antimicrobial peptides, and is mainly used in the study of periodontal diseases and immune-related oral diseases .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Policresulen

Cat. No.: HY-W129596

CAS No.: 101418-00-2

Target:

Virus Protease Dengue Virus

Research Areas:

Infection Inflammation/Immunology

Policresulen is a competitive inhibitor for DENV2 NS2B/NS3 protease with an IC₅₀ of 0.48 μg/mL. Policresulen can be used as a local hemostatic and antibacterial agent for research of cervical and vaginal inflammation, skin lesions, oral mucosa and gingival inflammation .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

D-Cateslytin

Cat. No.: HY-P11170

CAS No.: 3002053-77-9

Target:

Fungal

Research Areas:

Infection

D-Cateslytin is an antimicrobial peptide that exhibits potent inhibition activity against Candida albicans (MIC = 2.9 μM). D-Cateslytin can rapidly enter C. albicans, and shows no cytotoxicity to human gingival fibroblasts, and is stable in saliva. D-Cateslytin can be used for research on Candida albicans related diseases, such as oral candidosis .

Compare