47 Results for "

GlcCer

" in MedChemExpress (MCE) Product Catalog:
Products (47)

47 Results for "GlcCer" in MCE Product Catalog:

βGlcCer
βGlcCer
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Cat. No.: HY-152940
CAS No.: 887907-50-8
Synonyms: C24:1 β-glucosylceramide
Target:  

Drug Derivative PKC C-type Lectin-like Receptors (CTLRs)

Research Areas:  

Metabolic Disease Inflammation/Immunology

βGlcCer is a glycosphingolipid. βGlcCer directly increases the development and PKCα and PKCδ activation in mouse bone marrow-derived DCs (BMDCs) . β-GlcCer accumulating in Gaucher disease activates microglia through macrophage-inducible C-type lectin (Mincle) to induce phagocytosis of living neurons, which exacerbates Gaucher symptoms .
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C22-Ceramide (d18:1/22:0)
C22-Ceramide (d18:1/22:0)
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Cat. No.: HY-154831
CAS No.: 27888-44-4
Purity:  ≥98.0%
Synonyms: N-Behenoyl-D-erythro-sphingosine; C22-Ceramide; Cer d18:1/22:0
Target:  

Liposome

Research Areas:  

Cardiovascular Disease Metabolic Disease

C22-Ceramide (d18:1/22:0) (N-Behenoyl-D-erythro-sphingosine) is an ultra-long-chain ceramide containing a C22:0 behenoyl acyl chain. C22-Ceramide can be glycosylated via CGT-3 to form C22 glucosylceramide (C22 GlcCer), which in turn maintains clathrin membrane localization and lysosomal homeostasis, inhibits TOR signaling and promotes SKN-1 activation, thereby enhancing oxidative stress resistance and extending the lifespan of C. elegans. C22-Ceramide can be used in research on cardiometabolic diseases such as type 2 diabetes, obesity, dyslipidemia, coronary artery disease and thin-cap fibroatheroma (TCFA), as well as oxidative stress and aging-related studies .
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Mu-6S-Palm-β-Glc
Mu-6S-Palm-β-Glc
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Cat. No.: HY-145519
CAS No.: 229644-17-1
Target:  

Fluorescent Dye

Research Areas:  

Neurological Disease

Mu-6S-Palm-β-Glc is a fluorogenic substrate for palmitoyl-protein thioesterase (PPT). Mu-6S-Palm-β-Glc can be used for the research of neuronal ceroid lipofuscin disease in infants .
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AMP-Deoxynojirimycin
AMP-Deoxynojirimycin
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Cat. No.: HY-114615
CAS No.: 216758-20-2
Purity:  99.7%
Synonyms: AMP-DNM
Target:  

Glycosidase Glucosylceramide Synthase (GCS)

Research Areas:  

Neurological Disease

AMP-Deoxynojirimycin (AMP-DNM) is a potent ceramide glucosyltransferase and GCase 2 inhibitor. AMP-Deoxynojirimycin also is a GlcCer biosynthesis inhibitor .
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GlcCer (d18:1/18:0)
GlcCer (d18:1/18:0)
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Cat. No.: HY-170035
CAS No.: 95119-86-1
Synonyms: C18 Glucosyl(β) ceramide (d18:1/18:0); D-glucosyl-β-1,1' N-stearoyl-D-erythro-sphingosine
Target:  

Fungal Wnt β-catenin

Research Areas:  

Infection Neurological Disease Cancer

GlcCer (d18:1/18:0) (C18 Glucosyl(β) ceramide (d18:1/18:0)) is a glycosphingolipids that activates the Wnt/β-catenin pathway by targeting LRP6. GlcCer (d18:1/18:0) drives EMT, migration, invasion and GBA1-mediated liver cancer metastasis. GlcCer (d18:1/18:0) accumulates to impair lysosomal function and induce toxic α-synuclein aggregation. GlcCer (d18:1/18:0) supports growth, sporulation, germination and virulence in Penicillium digitatum. GlcCer (d18:1/18:0) is reduced in demyelinated mouse corpus callosum. GlcCer (d18:1/18:0) can be used for the research of liver cancer, synucleinopathies, fungal, Parkinson’s disease and Gaucher disease .
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UDP-Glc dehydrogenase (UGDH)
UDP-Glc dehydrogenase (UGDH)
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Cat. No.: HY-E70020
Target:  

Others

Research Areas:  

Others

UDP-Glc dehydrogenase (UGDH) catalyzes is a NAD+-dependent enzyme that catalyzes the two-fold oxidation of UDP-glucose (UDP-Glc) to produce UDP-glucuronic acid. UDP-Glc dehydrogenase (UGDH) is a key enzyme in the nucleotide-sugar interconversion pathway necessary for biosynthesis of many cell-wall polysaccharides .
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β-1,4-Galactosyltransferase 7
β-1,4-Galactosyltransferase 7
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Cat. No.: HY-E70138
Synonyms: EC:2.4.1.133; B4GALT7
β-1,4-Galactosyltransferase 7 has exclusive specificity for the donor substrate UDP-galactose and all transfer galactose in a β-1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. .
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UDP-sugar pyrophosphorylase (BlUSP)
UDP-sugar pyrophosphorylase (BlUSP)
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Cat. No.: HY-E70028
CAS No.: 223918-15-8
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

UDP-sugar pyrophosphorylase (BlUSP) is the enzyme capable of activating glucose-1-phosphate (Glc-1-P) to UDP-glucose (UDP-Glc). UDP-sugar pyrophosphorylase (BlUSP) catalyzes a reversible transfer of the uridyl group from UTP to sugar-1-phosphate, producing UDP-sugar and pyrophosphate (PPi) .
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Galactosylceramide
Galactosylceramide
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Cat. No.: HY-151240
CAS No.: 85305-88-0
Purity:  98%
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

Galactosylceramide (GalC) is a galactosylceramide that has been implicated in many physiological and pathological phenomena. For example, important lysosomal storage disorders such as Gaucher disease (GD) and neurodegenerative diseases are characterized by GlcCer accumulation.
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beta-Glc-TEG-Alkyne
beta-Glc-TEG-Alkyne
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Cat. No.: HY-151643
CAS No.: 1072903-76-4
Target:  

ADC Linkers

Research Areas:  

Others

beta-Glc-TEG-Alkyne is a click chemistry reagent containing an alkynes group. beta-Glc-TEG-Alkyne can be used for the research of various biochemical .
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Isoglobotriaose
Isoglobotriaose
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Cat. No.: HY-N10526
CAS No.: 41744-59-6
Synonyms: Gala-3Galb-4Glc
Category:  

Polysaccharides Microorganisms Saccharides

Target:  

Others

Isoglobotriaose (Gala-3Galb-4Glc) is a glycosphingolipid found in mammalian tissues. Isoglobotriaose is an analogue of Globotriaose, the ganglioside derivatives of them locate in difference position of small intestine, isoglobotriaosylceramide is restricted to the nonepithelial residue, while globotriaosylceramide is in both compartments .
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UDP-4-azido-4-deoxy-D-Glc disodium
UDP-4-azido-4-deoxy-D-Glc disodium
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Cat. No.: HY-177891
Synonyms: UDP-4N3-Glc disodium
Target:  

Nucleoside Antimetabolite/Analog

Research Areas:  

Others

UDP-4-azido-4-deoxy-D-Glc disodium is a sugar nucleotide.
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C6 NBD Phytoceramide
C6 NBD Phytoceramide
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Cat. No.: HY-D1573
CAS No.: 114301-99-4
Target:  

Fluorescent Dye

Research Areas:  

Others

C6 NBD Phytoceramide is a fluorescently labeled short-chain ceramide analog that can be recognized by mammalian GlcCer synthase (GCS) .
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D-threo-PPMP hydrochloride
D-threo-PPMP hydrochloride
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Cat. No.: HY-116535
CAS No.: 139889-65-9
Purity:  ≥98.0%
Target:  

Glucosylceramide Synthase (GCS)

Research Areas:  

Neurological Disease

D-threo-PPMP hydrochloride is a potent inhibitor of glucosylceramide (GlcCer) synthase. D-threo-PPMP hydrochloride can block karyokinesis and reduce cyst production .
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Heptasaccharide Glc4Xyl3
Heptasaccharide Glc4Xyl3
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Cat. No.: HY-125826
CAS No.: 121591-98-8
Category:  

Polysaccharides Microorganisms Metabolic Disease Disease Research Fields Saccharides

Target:  

Biochemical Assay Reagents

Heptasaccharide Glc4Xyl3, a covalent inhibitor of endo-xyloglucanases, is used for the identification and analysis of diverse xyloglucan-active enzymes in nature[1].
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Hydroxyvalerenic acid
Hydroxyvalerenic acid
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Cat. No.: HY-N7262
CAS No.: 1619-16-5
Category:  

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