94 Results for "

Gram positive pathogen

" in MedChemExpress (MCE) Product Catalog:
Products (94)

94 Results for "Gram positive pathogen" in MCE Product Catalog:

15
15 Publications Verification
Cat. No.: HY-B0925
CAS No.: 1173-88-2
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Oxacillin sodium salt is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens .
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7
7 Cited Publications
Cat. No.: HY-B0395C
CAS No.: 163253-35-8
Synonyms: DU6859a hydrate
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections .
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7
7 Cited Publications
Cat. No.: HY-B0395
CAS No.: 127254-12-0
Synonyms: DU6859a
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection .
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5
5 Cited Publications
Cat. No.: HY-B1156
CAS No.: 38821-53-3
Synonyms: Cefradine; SQ-11436
Target:  

Bacterial Antibiotic TOPK

Research Areas:  

Infection Inflammation/Immunology

Cephradine (Cefradine) is a broad-spectrum and orally active cephalosporin. Cephradine is active against both gram-positive and gram-negative pathogens. Cephradine is effective in eradicating most penicillinase-producing organisms. Cephradine has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK .
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3
3 Cited Publications
Cat. No.: HY-112579
CAS No.: 209467-52-7
Purity:  97.22%
Synonyms: Ro 63-9141; BAL 9141
Target:  

Bacterial Antibiotic

Research Areas:  

Infection Inflammation/Immunology

Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci with a MIC90 value of 2 μg/mL for MRSA. Ceftobiprole also inhibits gram-positive and gram-negative pathogens. Ceftobiprole can be used for the study of hospital-acquired pneumonia (excluding ventilator-associated pneumonia) and community-acquired pneumonia .
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2
2 Cited Publications
Cat. No.: HY-B0698A
CAS No.: 118081-34-8
Synonyms: Sch-39720 dihydrate
Research Areas:  

Infection

Ceftibuten (Sch-39720) dihydrate, an antibiotic, is an orally active cephalosporin, possesses potent activity in vitro against a wide range of gram-negative and certain gram-positive pathogens .
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2
2 Cited Publications
Cat. No.: HY-14855A
CAS No.: 1431699-67-0
Purity:  98.21%
Synonyms: (S)-TR 700; (S)-DA 7157
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

(S)-Tedizolid is the S-enantiomer of Tedizolid. Tedizolid is a novel oxazolidinone with activity against Gram-positive pathogens. (S)-Tedizolid is the less active isomer.
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2
2 Cited Publications
Cat. No.: HY-14737A
CAS No.: 400827-55-6
Purity:  98.88%
Synonyms: TAK-599 hydrate; PPI0903 hydrate
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Ceftaroline fosamil hydrate is a potent cephalosporin antibiotic. Ceftaroline fosamil hydrateshows broad-spectrum activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Streptococcus pneumoniae, and common Gram-negative organisms. Ceftaroline fosamil hydrate has anti-infective activity, and can be used for the research of complicated skin and skin structure infections (cSSSIs) and community-acquired bacterial pneumonia (CABP) .
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1
1 Cited Publications
Cat. No.: HY-111023
CAS No.: 951163-60-3
Purity:  99.43%
Synonyms: TG-873870 malate
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Nemonoxacin (TG-873870) malate is a nonfluorinated quinolone antibiotic. Nemonoxacin malate has broad-spectrum activity against Gram-positive, Gram-negative and atypical pathogens. Nemonoxacin malate can inhibit drug-resistant Streptococcus pneumoniae and Methicillin-resistant Staphylococcus aureus. Nemonoxacin malate can be used for the research of community-acquired pneumonia .
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1
1 Cited Publications
Cat. No.: HY-155333
CAS No.: 2001602-10-2
Target:  

Bacterial

Research Areas:  

Infection

Antibiofilm agent-1 is an antibacterial agent that inhibits growth of Gram-positive pathogens (WO2017011725A1; compound 17) .
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1
1 Cited Publications
Cat. No.: HY-139554A
Purity:  99.79%
Synonyms: KBP-7072 TFA
Target:  

Bacterial

Research Areas:  

Infection

Zifanocycline (KBP-7072) TFA is an orally active, semi-synthetic aminomethylcycline antibiotic that inhibits the normal function of bacterial ribosomes. Zifanocycline TFA has broad spectrum in vitro antimicrobial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline TFA is indicated for the study of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections .
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Cat. No.: HY-B0396
CAS No.: 161715-24-8
Synonyms: L084
Target:  

Antibiotic Bacterial OAT

Research Areas:  

Infection

Tebipenem pivoxil (L084 hydrobromide) is an orally active carbapenem Antibiotic. Tebipenem pivoxil acts as a substrate of OATP1A2 with high affinity for this transporter (Km = 41.1 μM) . Tebipenem pivoxil achieves intestinal absorption via carrier-mediated uptake and simple diffusion. Tebipenem pivoxil inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, multidrug-resistant bacteria, and pathogens producing extended-spectrum β-lactamases. Tebipenem pivoxil eliminates intestinal infection pathogens and reduces mortality in septic mice. Tebipenem pivoxil can be used in research related to bacterial pneumonia, severe gastrointestinal infections, bacterial sepsis, complicated urinary tract infections, and acute pyelonephritis .
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Cat. No.: HY-106574A
CAS No.: 252188-71-9
Purity:  95.70%
Synonyms: BAL5788 sodium
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

Ceftobiprole medocaril (BAL5788) sodium is the parenteral proagent of Ceftobiprole (HY-112579). Ceftobiprole is a parenteral pyrrolidinone cephalosporin. Ceftobiprole is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci. Ceftobiprole also inhibits gram-positive and gram-negative pathogens .
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Cat. No.: HY-141633
CAS No.: 25339-99-5
Purity:  ≥97.0%
Sucrose monolaurate is a glycolipid surfactant . Sucrose monolaurate interacts with bacterial DNA, disrupts cell membrane permeability, and exerts excellent inhibitory and bactericidal effects against a variety of foodborne pathogens (especially Gram-positive bacteria). Sucrose monolaurate significantly reduces liquid surface tension, and acts as a synergist for chlorine-based disinfectants in food cleaning and disinfection to improve the removal efficiency of pathogens on the surface of agricultural products .
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Cat. No.: HY-P5601
CAS No.: 214542-43-5
Target:  

Bacterial Fungal

Research Areas:  

Infection

Thanatin is an inducible cationic antimicrobial peptide. Thanatin is a pathogen-inducible single-disulfide-bond-containing β-hairpin AMP. Thanatin displays broad-spectrum activity against both Gram-negative and Gram-positive bacteria as well as against various species of fungi with MICs of 0.3-40 µM, 0.6-40 µM and 0.6-20 µM, respectively. Thanatin has the property of competitive replacement of divalent cations from bacterial outer membrane (OM), leading to OM disruption .
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Cat. No.: HY-A0279
CAS No.: 270076-60-3
Synonyms: Pristinamycine
Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF) .
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Cat. No.: HY-P5601A
Target:  

Bacterial Fungal

Research Areas:  

Infection

Thanatin TFA is an inducible cationic antimicrobial peptide. Thanatin TFA s a pathogen-inducible single-disulfide-bond-containing β-hairpin AMP. Thanatin TFA displays broad-spectrum activity against both Gram-negative and Gram-positive bacteria as well as against various species of fungi with MICs of 0.3-40 µM, 0.6-40 µM and 0.6-20 µM, respectively. Thanatin TFA has the property of competitive replacement of divalent cations from bacterial outer membrane (OM), leading to OM disruption .
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Cat. No.: HY-N7151
CAS No.: 108354-13-8
Aurachin D is an antibiotic and selective cytochrome bd oxidase inhibitor. Aurachin D exhibits inhibitory effects against Gram-positive bacteria and a small number of fungi, with an IC50 value of 0.1 μM against Escherichia coli and an IC50 value ranging from 0.13 to 33 μM against Mycobacterium tuberculosis. Aurachin D binds to and inhibits cytochrome bd oxidase, thereby blocking the electron transfer process, disrupting the respiratory chain and energy metabolism of pathogens. Aurachin D can be used in research related to leishmaniasis, malaria, Chagas disease, African trypanosomiasis, and tuberculosis [2] .
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Cat. No.: HY-16158
CAS No.: 3485-14-1
Synonyms: Wy-4508; Aminocyclohexylpenicillin; Ciclacillin
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Cyclacillin (Wy-4508) is an orally active aminopenicillin antibiotic, shows antibacterial activity against a wide range of gram-positive and gram-negative pathogens .
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Cat. No.: HY-103249
CAS No.: 303957-69-9
Purity:  98.08%
Synonyms: Reutericycline
Reutericyclin (Reutericycline) is an orally active antibacterial and anti-obesity agent that selectively inhibits Gram-positive bacteria. By selectively dissipating transmembrane potential, Reutericyclin exerts non-lytic bactericidal or bacteriostatic activity against pathogens such as Clostridium difficile and Staphylococcus aureus, and rapidly kills vegetative cells and spores of Clostridium difficile. Reutericyclin possesses favorable properties including resistance to enzymatic hydrolysis, iron-chelating function, and poor absorption by colonic epithelium. Reutericyclin not only eradicates staphylococcal biofilms and inhibits drug-resistant strains, but also counteracts Risperidone (HY-11018)-induced weight gain by inducing changes in gut microbiota composition and restoring energy utilization efficiency. Reutericyclin can be used in research related to Clostridium difficile infection, Risperidone-induced weight gain, and staphylococcal superficial skin infections .
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