38 Results for "

Guanidine

" in MedChemExpress (MCE) Product Catalog:
Products (38)

38 Results for "Guanidine" in MCE Product Catalog:

4
CHAPS
CHAPS
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4 Cited Publications
Cat. No.: HY-15435
CAS No.: 75621-03-3
Purity:  99.91%
Target:  

Exosomes Biochemical Assay Reagents

Research Areas:  

Others

CHAPS is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm-Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS is commonly used in research on the separation and purification of membrane proteins .
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4
CHAPS hydrate
CHAPS hydrate
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4 Cited Publications
Cat. No.: HY-15435A
CAS No.: 331717-45-4
Purity:  ≥98.0%
CHAPS hydrate is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS hydrate exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS hydrate stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm‑Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS hydrate is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS hydrate cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS hydrate is commonly used in research on the separation and purification of membrane proteins .
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3
Guanidine hydrochloride
Guanidine hydrochloride
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3 Cited Publications
Cat. No.: HY-B0178A
CAS No.: 50-01-1
Synonyms: Guanidinium chloride; Aminoformamidine hydrochloride
Category:  

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Biochemical Assay Reagents

Guanidine hydrochloride (Guanidinium chloride) is a strong protein denaturant. Guanidine hydrochloride causes proteins to assume a random coil conformation .
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3
Guanidine thiocyanate
Guanidine thiocyanate
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3 Cited Publications
Cat. No.: HY-D0841
CAS No.: 593-84-0
Category:  

Infection Natural Products Endogenous metabolite Disease Research Fields Cancer

Target:  

Endogenous Metabolite

Guanidine thiocyanate is a strong protein denaturant and potent inhibitor of nucleases. Guanidinium thiocyanate is a nucleic acid protector in the extraction of DNA and RNA from cells. Guanidine thiocyanate is a common component of buffers used for nucleic acid extraction .
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GMQ hydrochloride
GMQ hydrochloride
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1 Cited Publications
Cat. No.: HY-107757
CAS No.: 5361-15-9
Purity:  99.66%
Synonyms: 2-Guanidine-4-methylquinazoline hydrochloride
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

GMQ (hydrochloride) is a ASIC (acid-sensing ion) channel activator with an EC50 value of 1.83 mM for ASIC3 at pH 7.4. GMQ (hydrochloride) opens only ASIC3 but no other ASICs at pH 7.4. GMQ (hydrochloride) can be used for neurological disease research .
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Cylindrospermopsin
Cylindrospermopsin
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Cat. No.: HY-121360
CAS No.: 143545-90-8
Category:  

Microorganisms

Target:  

DNA/RNA Synthesis Reactive Oxygen Species (ROS)

Cylindrospermopsin, a cyanotoxin, is a polycyclic uracil derivative containing guanidine and sulfate groups, which can inhibit protein synthesis and covalently modify DNA or RNA. Cylindrospermopsin induces hepatocellular hypertrophy, renal cellular hypertrophy, intracellular reactive oxygen species (ROS), DNA strand breaks, mitochondrial hyperpolarisation, ultrastructural damage, and altered gene expression in liver, kidney, and intestinal cells. Cylindrospermopsin can be used in research including hepatocellular carcinoma and water quality testing .
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Triazabicyclodecene
Triazabicyclodecene
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Cat. No.: HY-59156
CAS No.: 5807-14-7
Triazabicyclodecene is a bicyclic guanidine compound that can serve as a pharmaceutical intermediate for the formation of amides or esters .
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Galegine hydrochloride
Galegine hydrochloride
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Cat. No.: HY-N0930B
CAS No.: 2368870-39-5
Category:  

Alkaloids Other Alkaloids Metabolic Disease 500 - Internal Server Error | MedChemExpress

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