1 Result for "

Gwt1p

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Gwt1p" in MCE Product Catalog:

Cat. No.: HY-187926
CAS No.: 2675491-09-3
Research Areas:  

Infection

Antimalarial agent 67 is an orally active inositol acyltransferase Gwt1p inhibitor and antimalarial agent, with IC50 values of 0.030 μM and 0.041 μM against P. falciparum 3D7 and K1 strains, respectively. Antimalarial agent 67 blocks inositol ring acylation by inhibiting the key enzyme Gwt1p in the GPI biosynthesis pathway of Plasmodium, thereby inhibiting parasite growth and maturation. Antimalarial agent 67 can be used for research on malaria [1].
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