20

Dexrazoxane

20 Publications Verification

Cat. No.: HY-B0581

CAS No.: 24584-09-6

Synonyms: ICRF-187; ADR-529; NSC-169780

Target:

Ferroptosis Apoptosis

Research Areas:

Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer

Dexrazoxane, as an intracellular iron chelating agent, reduces the formation of superoxide radicals and has cardioprotective, anti-inflammatory, antioxidant, anti-tumor and neuroprotective activities. Dexrazoxane inhibits ferroptosis of H9c2 cells by inhibiting HMGB1. Dexrazoxane induces DNA damage and apoptosis in human fibrosarcoma cells .

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8

ML115

8 Cited Publications

Cat. No.: HY-111152

CAS No.: 912798-42-6

Purity: 99.89%

Target:

STAT

Research Areas:

Cancer

ML115, a molecular probe of the signal transducer, is a selective STAT3 agonist, with an EC₅₀ of 2 nM. ML115 increases the expression of BCL3, a known STAT3-dependent oncogene. ML115 is inactive against the related STAT1, STAT5 and NF-κB anti-targets. ML115 counteracts the effects of Ginsenoside Rc (HY-N0042) on cell viability and inflammatory responses in LPS (HY-D1056)-stimulated H9c2 and RAW264.7 cells, while altering oxidative stress markers. ML115 can be used for the study of breast and prostate cancers .

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4

Tarenflurbil

4 Cited Publications

Cat. No.: HY-10291

CAS No.: 51543-40-9

Purity: 99.58%

Synonyms: (R)-Flurbiprofen; MPC7869

Target:

RAR/RXR Autophagy

Research Areas:

Infection Neurological Disease Inflammation/Immunology Cancer

Tarenflurbil ((R)-Flurbiprofen) is the R-enantiomer of the racemate NSAID Flurbiprofen, Tarenflurbil ((R)-Flurbiprofen) inhibits the binding of [ ³H]9-cis-RA to RXRα LBD with IC₅₀ of 75 μM. Tarenflurbil can be used for Alzheimer's disease research.

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3

CD9 Antibody

3 Cited Publications

Cat. No.: HY-P80610

Synonyms: CD9; MIC3; TSPAN29; GIG2; CD9 antigen; 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; MRP-1; Tetraspanin-29; Tspan-29; p24; CD antigen CD9

Host:

Rabbit

Application:

WB, IHC-P, ICC/IF, IP, FC

Reactivity:

Human, Mouse, Rat

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3

CD9 Antibody (YA7185)

3 Cited Publications

Cat. No.: HY-P80610A

Synonyms: CD9; MIC3; TSPAN29; GIG2; CD9 antigen; 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; MRP-1; Tetraspanin-29; Tspan-29; p24; CD antigen CD9

Host:

Rabbit

Application:

WB, IHC-P, ICC/IF, IP, FC

Reactivity:

Human, Mouse, Rat

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