country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

11 Results for "

H187

" in MedChemExpress (MCE) Product Catalog:

Products (11)

Sort by :

Categories

By Targets

Products

Cerberin

Cat. No.: HY-W779529

CAS No.: 25633-33-4

Synonyms: 2'-Acetylneriifolin

Target:

Na+/K+ ATPase

Research Areas:

Cancer

Cerberin is a cardiac glycoside that has been found in C. odollam and has cytotoxic and cardiac modulatory activities. It is cytotoxic to KB and NCI H187 cancer cells (IC₅₀s=1.92 and 1.24 μg/mL).1 Cerberin inhibits Na+/K+-ATPase, increasing intracellular sodium levels and action potential duration in cardiac cells.

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Miaosporone A

Cat. No.: HY-145379

CAS No.: 3039491-16-9

Category:

Infection Quinones Monophenols Anthraquinones Phenols Endogenous metabolite Disease Research Fields

Target:

Parasite Endogenous Metabolite

Miaosporone A, an angucyclic quinone, exhibits antimalarial activity against Plasmodium falciparum K1 and antibacterial activity against Mycobacterium tuberculosis with respective IC₅₀ values of 2.5 and 2.4 μM and displays cytotoxic activities against both cancerous (MCF-7 and NCI-H187) and nonmalignant (Vero) cells .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Carbazomycin D

Cat. No.: HY-N12232

CAS No.: 108073-63-8

Category:

Alkaloids Microorganisms Indole Alkaloids

Target:

Parasite Bacterial

Carbazomycin D exhibits antituberculosis and antimalarial activities, that inhibits Plasmodium falciparum with an IC₅₀ > 10 μg/mL, inhibits Mycobacterium tuberculosis with MIC of 25 μg/mL. Carbazomycin D exhibits cytotoxicity in cell MCF-7, KB, NCI-H187 and Vero, with IC₅₀s of 21.3, 33.2, 12.9, and 34.3 μg/mL, respectively .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Versimide

Cat. No.: HY-N15652

CAS No.: 30270-17-8

Category:

Alkaloids Microorganisms Pyrrole Alkaloids

Target:

Biochemical Assay Reagents

Versimide (Compound 15) can be isolated from the insect pathogenic fungus Gibellula sp. BCC36964. Versimide exhibits cytotoxicity in cell lines including MCF-7, KB, NCI-H187, and Vero with IC₅₀s of 3.59, 4.83, 1.89, and 3.49 μg/mL, respectively, demonstrating its anticancer activity .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

BM-1074

Cat. No.: HY-13846

CAS No.: 1391108-10-3

Target:

Bcl-2 Family Apoptosis

Research Areas:

Cancer

BM-1074 is a potent and specific Bcl-2/Bcl-xL inhibitor with K_i values of < 1 nM and IC₅₀ values of 1.8 nM and 6.9 nM for Bcl-2 and Bcl-xL, respectively. BM-1074 induces apoptosis, and exhibits antiproliferative activity against four small-cell lung cancer cell lines (H146, H1963, H187 and H1417) with IC₅₀ values of 1-2 nM .

Compare