2 Results for "

H3K27me2

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "H3K27me2" in MCE Product Catalog:

Cat. No.: HY-P2253
Target:  

Histone Demethylase

Research Areas:  

Cancer

H3K27(Me2) (15-34), a histone peptide, is a repressive chromatin mark derived from human histone. Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the methylation of H3K27(Me) .
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Cat. No.: HY-122595
CAS No.: 1377997-28-8
Research Areas:  

Cancer

EZH2-IN-1 (compound 3) is a selective and SAM-competitive EZH2 and EZH1 inhibitor with an IC50s of 32 nM, 197 nM and 213 nM for EZH2wt, EZH2 Y641N mutant and EZH1, respectively. EZH2-IN-1 reduces bulk H3K27me3 and H3K27me2 levels. EZH2-IN-1 has the potential for diffuse large B cell lymphoma research .
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