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14 Results for "

H9c2 cells

" in MedChemExpress (MCE) Product Catalog:

Products (14)

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Dexrazoxane

20 Publications Verification

Cat. No.: HY-B0581

CAS No.: 24584-09-6

Synonyms: ICRF-187; ADR-529; NSC-169780

Target:

Ferroptosis Apoptosis

Research Areas:

Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer

Dexrazoxane, as an intracellular iron chelating agent, reduces the formation of superoxide radicals and has cardioprotective, anti-inflammatory, antioxidant, anti-tumor and neuroprotective activities. Dexrazoxane inhibits ferroptosis of H9c2 cells by inhibiting HMGB1. Dexrazoxane induces DNA damage and apoptosis in human fibrosarcoma cells .

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ML115

8 Cited Publications

Cat. No.: HY-111152

CAS No.: 912798-42-6

Purity: 99.89%

Target:

STAT

Research Areas:

Cancer

ML115, a molecular probe of the signal transducer, is a selective STAT3 agonist, with an EC₅₀ of 2 nM. ML115 increases the expression of BCL3, a known STAT3-dependent oncogene. ML115 is inactive against the related STAT1, STAT5 and NF-κB anti-targets. ML115 counteracts the effects of Ginsenoside Rc (HY-N0042) on cell viability and inflammatory responses in LPS (HY-D1056)-stimulated H9c2 and RAW264.7 cells, while altering oxidative stress markers. ML115 can be used for the study of breast and prostate cancers .

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EUK-134

1 Cited Publications

Cat. No.: HY-100594

CAS No.: 81065-76-1

Purity: 98.27%

Target:

NF-κB

Research Areas:

Cardiovascular Disease

EUK-134, a synthetic superoxide dismutase and catalase mimetic, protects rat kidneys from ischemia-reperfusion-induced damage. EUK-134 is a superoxide dismutase (SOD) mimetics (SODm) with catalase activity. EUK-134 is a mitoprotective antioxidant. EUK-134 reduces the expression of NF-κB, MDA level, and protein carbonylation in H9C2 cells .

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