country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

3 Results for "

HBMEC

" in MedChemExpress (MCE) Product Catalog:

Products (3)

Sort by :

Categories

By Targets

Species:

Tags:

Sources:

Products

HSP90B1 Protein, Human (His, Strep)

1 Cited Publications

Cat. No.: HY-P703226

Purity: ≥ 90%, as determined by reducing SDS-PAGE.

Synonyms: HSP90B1; HEL35; Prev. TRA1; Heat Shock Protein 90kDa Beta Family Member 1; Endoplasmin; Stress-Inducible Tumor Rejection Antigen Gp96; GRP94; Endothelial Cell (HBMEC) Glycoprotein; Heat Shock Protein 90 KDa Beta Member 1; Epididymis Luminal Protein 35; GP

Species:

Human

Source:

E. coli

Compare

Please select quantity

August 31

Get Quote

View All Sizes

AM9928

Cat. No.: HY-182639

CAS No.: 1869033-49-7

Target:

Exosomes MAGL Interleukin Related VEGFR

Research Areas:

Cancer

AM9928 is a monoacylglycerol lipase (MAGL) inhibitor with IC₅₀ and K_i values of 8.9 nM and 7.3 nM, respectively. AM9928 blocks the adhesion and migration of triple-negative breast cancer (TNBC) cells, and inhibits the secretion of IL-6, IL-8 and VEGF-A by TNBC cells. AM9928 suppresses the activation of human brain microvascular endothelial cells (HBMECs) induced by TNBC-derived exosomes, and reduces the secretion of IL-8 and VEGF-A by HBMECs. AM9928 attenuates changes in blood-brain barrier permeability, inhibits tumor growth in the mammary fat pad, and reduces brain colonization of TNBC. AM9928 can be used in studies related to triple-negative breast cancer .

Compare