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318 Results for "

HCT

" in MedChemExpress (MCE) Product Catalog:

Products (318)

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GDC-0623

11 Publications Verification

Cat. No.: HY-15610

CAS No.: 1168091-68-6

Purity: 98.74%

Synonyms: RG 7421; MEK inhibitor 1

Target:

MEK Apoptosis

Research Areas:

Cancer

GDC-0623 (RG 7421) is a potent, ATP-uncompetitive inhibitor of MEK1 (K_i=0.13 nM, +ATP), and displays 6-fold weaker potency against HCT116 (KRAS (G13D), EC₅₀=42 nM) versus A375 (BRAF ^V600E, EC₅₀=7 nM).

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August 31

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Kinetin riboside

4 Cited Publications

Cat. No.: HY-101055

CAS No.: 4338-47-0

Purity: 99.88%

Synonyms: N6-Furfuryladenosine

Target:

Apoptosis

Research Areas:

Neurological Disease Cancer

Kinetin riboside, a cytokinin analog, can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells with an IC₅₀ of 2.5 μM.

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MSN-125

4 Cited Publications

Cat. No.: HY-120079

CAS No.: 1592908-16-1

Purity: 99.00%

Target:

Bcl-2 Family Apoptosis

Research Areas:

Cancer

MSN-125 is a potent Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) with an IC₅₀ of 4 μM. MSN-125 potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity .

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