285 Results for "

HCT-116

" in MedChemExpress (MCE) Product Catalog:
Products (285)

285 Results for "HCT-116" in MCE Product Catalog:

11
11 Publications Verification
Cat. No.: HY-15610
CAS No.: 1168091-68-6
Purity:  98.74%
Synonyms: RG 7421; MEK inhibitor 1
Target:  

MEK Apoptosis

Research Areas:  

Cancer

GDC-0623 (RG 7421) is a potent, ATP-uncompetitive inhibitor of MEK1 (Ki=0.13 nM, +ATP), and displays 6-fold weaker potency against HCT116 (KRAS (G13D), EC50=42 nM) versus A375 (BRAF V600E, EC50=7 nM).
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4
4 Cited Publications
Cat. No.: HY-120079
CAS No.: 1592908-16-1
Purity:  99.00%
Target:  

Bcl-2 Family Apoptosis

Research Areas:  

Cancer

MSN-125 is a potent Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) with an IC50 of 4 μM. MSN-125 potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity .
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3
3 Cited Publications
Cat. No.: HY-N2409
CAS No.: 528-53-0
Category:  

Cardiovascular Disease Plants Other Families Extract Solanaceae Extract Anthocyans Flavonoids 500 - Internal Server Error | MedChemExpress

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