12 Results for "

HEL cells

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "HEL cells" in MCE Product Catalog:

1
AB25583
AB25583
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1 Cited Publications
Cat. No.: HY-162859
CAS No.: 2565637-94-5
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

AB25583 is a Polθ helicase (Polθ-hel) small molecule inhibitor, with an IC50 value of 6 nM. AB25583 selectively kills BRCA1/2 deficient cells and works in synergy with Olaparib (HY-10162) in cancer cells carrying pathogenic BRCA1/2 mutations. AB25583 can be used for tumor research .
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ZT55
ZT55
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Cat. No.: HY-124727
CAS No.: 2138488-38-5
Purity:  99.51%
Target:  

JAK Apoptosis

Research Areas:  

Cancer

ZT55 is an orally active and highly-selective JAK2 inhibitor with an IC50 value of 0.031 μM. ZT55 inhibits the proliferation of JAK2 V617F-expressing HEL cell lines and induces apoptosis and cycle arrest. ZT-55 also effectively inhibits the growth of HEL xenograft tumours in a mice model. ZT-55 can be used in studies of myeloproliferative neoplasms, polycythemia vera and primary thrombocythemia .
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BAY 73-1449
BAY 73-1449
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Cat. No.: HY-118941
CAS No.: 693790-96-4
Purity:  99.99%
Target:  

Prostaglandin Receptor

Research Areas:  

Cardiovascular Disease

BAY 73-1449 is a selective antagonist of prostacyclin receptor (IP), with high potency (IC50 of less than 0.1 nM) in cAMP assays in Human HEL cells and rat DRG. BAY 73-1449 can be used in the research of lowering blood pressure .
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Ajoene
Ajoene
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Cat. No.: HY-106784
CAS No.: 92285-01-3
Purity:  ≥99.0%
Category:  

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