4 Results for "

HEXIM1

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "HEXIM1" in MCE Product Catalog:

Cat. No.: HY-RS06145
Research Areas:  

Others

HEXIM1 Human Pre-designed siRNA Set A contains three designed siRNAs for HEXIM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P811822
Synonyms: CLP1, EDG1, HIS1, MAQ1, HEXIM1, Protein HEXIM1, Cardiac lineage protein 1, Estrogen down-regulated gene 1 protein, Hexamethylene bis-acetamide-inducible protein 1, Menage a quatre protein 1

Host:  

Mouse

Application:  

WB, FC, ICC/IF, IHC-P

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P811822A
Synonyms: CLP1, EDG1, HIS1, MAQ1, HEXIM1, Protein HEXIM1, Cardiac lineage protein 1, Estrogen down-regulated gene 1 protein, Hexamethylene bis-acetamide-inducible protein 1, Menage a quatre protein 1

Host:  

Mouse

Application:  

WB, FC, ICC/IF, IHC-P

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-184865
CAS No.: 3032493-76-5
Research Areas:  

Cancer

Anticancer agent 340 is an orally active antitumor agent. Anticancer agent 340 can bind to both the androgen receptor (AR) and BRD4 protein simultaneously, dose-dependently inducing the formation of the AR-BRD4 ternary complex, inhibiting the expression of the downstream target gene HEXIM1 (Gene X), and activating the Caspase 3/7 pathway to initiate apoptosis. Its proliferation inhibition and apoptosis activities are both significantly AR expression-dependent. Anticancer agent 340 can be used to study AR/BRD4 driven malignancies such as castration-resistant prostate cancer (CRPC) [1].
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