55 Results for "

HIV entry

" in MedChemExpress (MCE) Product Catalog:
Products (55)

55 Results for "HIV entry" in MCE Product Catalog:

8
8 Publications Verification
Cat. No.: HY-N4100
CAS No.: 4192-90-9
Trilobatin, a natural sweetener derived from Lithocarpus polystachyus Rehd , Trilobatin is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope . Neuroprotective effects . Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells .
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4
4 Cited Publications
Cat. No.: HY-P1034
CAS No.: 106362-34-9
Synonyms: D-Ala-peptide T-amide; Adaptavir
Target:  

CCR HIV

Research Areas:  

Infection Endocrinology

DAPTA is a synthetic peptide, functions as a viral entry inhibitor by targeting selectively CCR5, and shows potent anti-HIV activities.
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2
2 Cited Publications
Cat. No.: HY-138102
CAS No.: 52869-18-8
Purity:  98.01%
Target:  

SARS-CoV

Research Areas:  

Infection

SSAA09E3 is a SARS-CoV entry inhibitor that inhibits SARS/HIV pseudotyped virus entry with an EC50 of 9.7 μM in 293T cells and inhibits SARS-CoV infection of Vero cells with an EC50 of 0.15 μM .
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2
2 Cited Publications
Cat. No.: HY-P2537
CAS No.: 229961-08-4
Research Areas:  

Others

Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect .
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Cat. No.: HY-134809
CAS No.: 182316-44-5
Purity:  98.45%
Synonyms: CADA
Target:  

HIV

Research Areas:  

Infection Inflammation/Immunology

Cyclotriazadisulfonamide (CADA) is a specific CD4-targeted HIV entry inhibitors. Cyclotriazadisulfonamide (CADA) inhibits the co-translational translocation of human CD4 (huCD4) into the ER lumen in a signal peptide (SP)-dependent way. Cyclotriazadisulfonamide is also a Sec61 translocon inhibitor .
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Cat. No.: HY-P991069
CAS No.: 1412901-55-3

Target:  

HIV

Research Areas:  

Infection

VRC-01 is a broadly neutralizing IgG1 monoclonal antibody that targets HIV-1 envelope glycoprotein gp120 Protein. VRC-01 blocks HIV-1 viral entry by mimicking CD4 receptor interaction with HIV-1 gp120 and neutralizes broad HIV-1 clades. VRC-01 can be used for the research of HIV-1 infection .
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Cat. No.: HY-P2988B
CAS No.: 9001-67-6
Target:  

Bacterial HIV

Research Areas:  

Infection

Neuraminidase, arthrobacter ureafaciens is a neuraminidase derived from Arthrobacter ureafaciens. Neuraminidase, arthrobacter ureafaciens catalyzes the removal of sialic acid residues from cell surfaces and viral glycoconjugates. Neuraminidase, arthrobacter ureafaciens enhances HIV-1-mediated syncytium formation and promotes the viral binding and entry steps in the HIV-1 replication cycle .
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Cat. No.: HY-P1066
CAS No.: 217082-57-0
Research Areas:  

Infection

Apelin-17(human, bovine) is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-17(human, bovine) binds to human APJ receptors expressed in HEK 293 cells (pIC50=9.02). Apelin-17(human, bovine) inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ .
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Cat. No.: HY-124619
CAS No.: 186452-09-5
Purity:  99.79%
Target:  

EAAT HIV

Research Areas:  

Neurological Disease

GPI-1046 is an orally active, antibiotic-free immunophilin ligand that reduces ethanol intake by upregulating glutamate transporter 1 (GLT1) in the prefrontal cortex (PFC) and nucleus accumbens core (NAc-core). GPI-1046 improves human immunodeficiency virus (HIV)-associated sensory neuropathy (HIV-SN) by attenuating store-operated calcium (SOC) entry. GPI-1046 has neuroprotective activity .
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Cat. No.: HY-103365
CAS No.: 1216540-18-9
Synonyms: VUF2274 hydrochloride
Target:  

CMV CCR

Research Areas:  

Infection

BX-513 hydrochloride (VUF2274 hydrochloride) is a CCR1 antagonist that inhibits chemokine binding and blocks US28 signaling. BX-513 hydrochloride inhibits human CCR1 with a Ki of 40 nM. BX-513 hydrochloride blocks CCL3-mediated signaling/chemotaxis, CCR1-mediated chemokine signaling, calcium mobilization, extracellular acidification, and US28-mediated HIV entry, with an IC50 of 4.9 μM. BX-513 hydrochloride can be used for research on hcmv infection .
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Cat. No.: HY-115488A
CAS No.: 1859189-55-1
Target:  

HIV

Research Areas:  

Infection

BNM-III-170, CD4-mimeticcompound, is an anti-HIV-1 agent. BNM-III-170 binds to the Phe43 cavity of HIV 1 gp120. BNM-III-170 can inhibits HIV-1 viral entry into target cells. BNM-III-170 can be used for the research of HIV-1 infection .
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Cat. No.: HY-P1064
CAS No.: 252642-12-9
Apelin-36(human) is an endogenous orphan G protein-coupled receptor APJ agonist, with an EC50 of 20 nM. Apelin-36(human) shows high affinity to human APJ receptors expressed in HEK 293 cells (pIC50=8.61). Apelin-36 has been linked to two major types of biological activities: cardiovascular and metabolic. Apelin-36(human) inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ .
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Cat. No.: HY-100039
CAS No.: 144217-65-2
Purity:  98.96%
Target:  

HIV

Research Areas:  

Infection

YYA-021 is a small-molecule CD4 mimic that inhibits HIV entry, with high anti-HIV activity and low cytotoxicity .
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Cat. No.: HY-P991246

Target:  

Virus Protease HIV

Research Areas:  

Infection

VRC01LS is a humanized monoclonal antibody inhibitor targeting the CD4-binding site of HIV-1 envelope glycoprotein (Env). VRC01LS blocks the binding of HIV-1 to host cell CD4 receptor, inhibiting viral entry. VRC01LS is promising for research of HIV-1 infection .
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Cat. No.: HY-107401
CAS No.: 370893-06-4
Synonyms: SCH-351125
Target:  

HIV CCR Calcium Channel

Research Areas:  

Infection

Ancriviroc (SCH-351125) is an orally active CCR5 antagonist with an IC50 value of 13 nM against hCCR5. Ancriviroc specifically binds to hCCR5, blocks ligand-induced signal transduction, calcium influx, GTPγS binding, chemotaxis, ligand binding, and HIV-1 entry, induces conformational changes in CCR5, and inhibits infection and replication of R5-tropic HIV-1 .
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Cat. No.: HY-76648
CAS No.: 333353-44-9
Target:  

HIV

Research Areas:  

Infection

NBD-556, a CD4 mimetic, is a potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction. NBD-556 shows potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels .
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Cat. No.: HY-P1065
CAS No.: 230299-95-3
Apelin-36(rat, mouse) is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-36(rat, mouse) binds to APJ receptors with an IC50 of 5.4 nM, and potently inhibits cAMP production with an EC50 of 0.52 nM. Apelin-36(rat, mouse) blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ .
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Cat. No.: HY-125183
CAS No.: 2974489-09-1
Target:  

HIV

Research Areas:  

Infection

BMS-818251 is a HIV-1 attachment and entry inhibitor. BMS-818251 binds to HIV-1 Env gp120, interferes with viral attachment and entry processes, and inhibits HIV-1 viral replication. BMS-818251 can be used in studies related to HIV-1 infection .
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Cat. No.: HY-P99028
CAS No.: 680188-33-4
Synonyms: TMB-355; TNX-355

Target:  

HIV

Research Areas:  

Infection

Ibalizumab (TMB-355) is a humanized anti-CD4 IgG4 monoclonal antibody. Ibalizumab prevents HIV cell entry by binding to CD4 receptor. Ibalizumab can be used for the research of infection, such as HIV-1 infection .
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Cat. No.: HY-P1064A
Apelin-36(human) TFA is an endogenous orphan G protein-coupled receptor APJ agonist, with an EC50 of 20 nM. Apelin-36(human) TFA shows high affinity to human APJ receptors expressed in HEK 293 cells (pIC550=8.61). Apelin-36(human) TFA has been linked to two major types of biological activities: cardiovascular and metabolic. Apelin-36(human) TFA inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ .
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