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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
HK3
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "HK3" in MCE Product Catalog:
Cat. No.: HY-RS06194
Target:
Research Areas:
HK3 Human Pre-designed siRNA Set A contains three designed siRNAs for HK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19297
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Hk3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hk3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25788
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Hk3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Hk3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-170799
CAS No.: 2127358-36-3
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Research Areas:
HNC-1664 is the orally active inhibitor for RNA-dependent RNA polymerase (RdRP). HNC-1664 exhibits broad-spectrum antiviral activity against coronavirus (SARS-CoV-2 wildtype and its mutants XBB.1.18, HK.3.1, BF.7.14, BA.1HCoV-229E, HCoV-OC43) and arenavirus. HNC-1664 exhibits anti-infectious activity in SARS-CoV-2 Delta infected mouse models .
Cat. No.: HY-P74881
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: HK3; HK III; Hexokinase 3; HKIII; Hexokinase 3 (White Cell); ATP:D-Hexose 6-Phosphotransferase; Hexokinase Type III; Phosphotransferase; Hexokinase-3; Hexokinase III; Hexokinase-C; HXK3
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-RS06289
Target:
Research Areas:
HOOK3 Human Pre-designed siRNA Set A contains three designed siRNAs for HOOK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07381
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Research Areas:
KLK3 Human Pre-designed siRNA Set A contains three designed siRNAs for KLK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-183809
CAS No.: 3124329-46-7
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Research Areas:
ZSW is a hexokinase 2 (HK2) inhibitor with human HK2 IC50 of 0.48 μM, human HK2 Ka of 252.00 μM, and selectivity over HK3 and GCK. ZSW binds directly to HK2, inhibits its enzymatic activity, modulates macrophage phenotypes through glycolysis inhibition, and inhibits NF-κB nuclear translocation by preventing IκBα phosphorylation and degradation. ZSW alleviates inflammatory bowel disease (IBD) and improves the intestinal inflammatory state of IBD mice. ZSW can be used for the research of inflammatory bowel disease .
Cat. No.: HY-189292
Research Areas:
HK2-IN-5 is a selective hexokinase 2 (HK2) inhibitor with an IC50 of 1.17 μM against HK2 enzymatic activity. HK2-IN-5 shows weak inhibition against HK3 and GCK (HK4). By inhibiting HK2, HK2-IN-5 induces a decrease in mitochondrial membrane potential (ΔΨm) and accumulation of reactive oxygen species (ROS), leading to mitochondrial dysfunction and oxidative stress, and its antiproliferative effect is mainly dependent on HK2. HK2-IN-5 can be used in research related to triple-negative breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
