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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
HMG499
" in MedChemExpress (MCE) Product Catalog:
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1 Results for "HMG499" in MCE Product Catalog:
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HMG499 is an orally active HMGCR degrader with an EC50 of 0.39 μM. HMG499 induces HMG-CoA reductase degradation through Insig-dependent ubiquitination and proteasomal degradation pathways. HMG499, alone or in combination with Lovastatin (HY-N0504), reduces in vivo cholesterol and triglyceride levels and alleviates atherosclerotic plaques. HMG499 can be used in research related to hypercholesterolemia, hyperlipidemia, and atherosclerosis .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
