![Pyrimido[1,2-a]purin-10(1H)-one-13C3](https://file.medchemexpress.com/product_pic/hy-w777806.gif "Click to View Pyrimido[1,2-a]purin-10(1H)-one-13C3 Product Detail")
Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
HONE-1
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "HONE-1" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-N6954
CAS No.: 76996-27-5
Cat. No.: HY-N1261
CAS No.: 905929-95-5
Category:
Alkaloids Plant Scutellaria barbata D. Don Extract Pyridine Alkaloids Disease Research Fields Cancer Labiatae Extract
Target:
Cat. No.: HY-N8462
CAS No.: 1206805-30-2
Synonyms: Scutebatin C
Category:
Alkaloids Plant Scutellaria barbata D. Don Extract Other Alkaloids Pyridine Alkaloids Labiatae Extract
Target:
Cat. No.: HY-N6954R
CAS No.: 76996-27-5
Category:
Plant Xanthones Guttiferae Extract Phenols Polyphenols Garcinia oblongifolia Champ. ex Benth. Extract Other Families Extract
Target:
Target:
Research Areas:
QO-40, a pyrazolo[1,5-a]pyrimidine-7(4H)-one (PPO) derivative, is a KCNQ2/KCNQ3 K + channels activator with an EC50 of 6.94 μM. QO-40 stimulated Ca 2+-activated K + current (IK(Ca)) with an EC50 value of 2.3 μM in pituitary GH3 lactotrophs [1] .
Cat. No.: HY-W777806
CAS No.: 1246815-92-8
Cat. No.: HY-181493
Research Areas:
VEGFR-2-IN-81 is a thiazole-based isoquinolin-1(2H)-one derivative and an VEGFR-2 inhibitor with IC50 of 1.94 μM. VEGFR-2-IN-81 exhibits significant selective cytotoxicity against colorectal cancer cells (IC50 = 7.75 μM). VEGFR-2-IN-81 exerts anti-colorectal cancer effects by inducing apoptosis, elevating intracellular ROS levels and reducing mitochondrial transmembrane potential. VEGFR-2-IN-81 can be used for the research of colorectal cancer, lung cancer, breast cancer, liver cancer [1].
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
