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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
HSP76
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "HSP76" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-P72238
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSP90AA1; Heat Shock 86 KDa; Prev. HSPC1; FLJ31884; Prev. HSPCA; HSP90A; Prev. HSPCAL4; HSP 86; HSP90N; HSP86; HSP89; LAP-2; HSP90; Heat Shock Protein 90kDa Alpha Family Class A Member 1; Heat Shock Protein 90kDa Alpha (Cytosolic), Class A Member 1; Heat
Species:
Human
Source:
E. coli
2
2 Cited Publications
Research Areas:
HS-276 is an orally active, potent and highly selective TAK1 inhibitor, with a Ki of 2.5 nM. HS-276 shows significant inhibition of TAK1, CLK2, GCK, ULK2, MAP4K5, IRAK1, NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC50 values of 8.25, 29, 33, 63, 125, 264, 270, 810, 1280, and 5585 nM, respectively. HS-276 reduces the expression of TNF, IL-6, and IL-1β. HS-276 can be used for rheumatoid arthritis (RA) research .
1
1 Cited Publications
Cat. No.: HY-P701386
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSPBP1; HSP70-Interacting Protein 2; HSPA (HSP70) Binding Protein 1; HSP70-Interacting Protein 1; FES1; HSP70-Binding Protein 2; HSPA (Heat Shock 70kDa) Binding Protein, Cytoplasmic Cochaperone 1; HSPBP2; Heat Shock Protein-Binding Protein 1; HSPBP1; HSP7
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P73915
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSPA8; Epididymis Secretory Sperm Binding Protein Li 72p; Prev. HSPA10; Constitutive Heat Shock Protein 70; HSC70; Epididymis Luminal Protein 33; HSP73; Heat Shock Cognate Protein 54; Heat Shock Cognate 71 KDa Protein; Heat Shock 70kd Protein 10; HSC71; Heat Shock 70kD Protein 8; Lipopolysaccharide-Associated Protein 1; HSPA8 Protein; Heat Shock Protein Family A Member 8; CDNA FLJ77848; Heat Shock 70 KDa Protein 8; HEL-S-72p; Heat Shock 70kDa Protein 8; HSC54; LPS-Associated Protein 1; HSP71; HEL-33; NIP71; LAP-1; LAP1; Heat Shock Protein Family A (HSP70) Member 8; N-Myristoyltransferase Inhibitor Protein 71
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P74877
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HSPA1A; Heat Shock 70 KDa Protein 1/2; Prev. HSPA1; Heat Shock 70 KDa Protein 2; HSP70-1; Heat Shock 70kDa Protein 1B; Heat Shock 70kDa Protein 1A; Heat Shock-Induced Protein; Epididymis Secretory Sperm Binding Protein; HSP70-1/HSP70-2; Heat Shock Protein Family A Member 1A; HSP70.1/HSP70.2; Epididymis Secretory Protein Li 103; HEL-S-103; Heat Shock 70 KDa Protein 1A; HSP70-1A; Heat Shock 70 KDa Protein 1; HSP70-2; Heat Shock 70kD Protein 1A; HSP70.2; HSP70.1; HSP70I; HSP72; HSPA1B; DnaK-Type Molecular Chaperone HSP70-1; HSP70; Heat Shock 70 KDa Protein 1A/1B; HSX70; Heat Shock Protein Family A (HSP70) Member 1A; Heat Shock 70 KDa Protein 1B
Species:
Human
Source:
HEK293
Cat. No.: HY-RS06435
Target:
Research Areas:
HSPA6 Human Pre-designed siRNA Set A contains three designed siRNAs for HSPA6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS06441
Target:
Research Areas:
HSPB6 Human Pre-designed siRNA Set A contains three designed siRNAs for HSPB6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-181147
CAS No.: 3131328-62-3
PROTAC HSP70 Degrader-1 (compound C4) is a cytosolic HSP70 PROTAC degrader that can engage CRBN to form a ternary complex. PROTAC HSP70 Degrader-1 mediates ubiquitination and proteasomal degradation of cytosolic HSP70. PROTAC HSP70 Degrader-1 exhibits cytotoxic activity against cancer cells, suppressing tumor cell proliferation and inducing apoptosis in combination with DTHIB. PROTAC HSP70 Degrader-1 can be used for the research of colon cancer and leukemia .
Cat. No.: HY-181148
CAS No.: 952738-81-7
Research Areas:
HSP70 ligand 1, a HSP70 ligand, is a ligand for the target protein of PROTAC. HSP70 ligand 1 can be used to synthesize PROTAC HSP70 Degrader-1 (HY-181147) .
Cat. No.: HY-187564
Target:
Research Areas:
HSP70 ligand 3 is a purine nucleoside intermediate that can serve as an HSP70 ligand for the synthesis of HSP70-based HEMTACs, such as HEMTAC AR degrader-1 (HY-187229) .
Cat. No.: HY-188167
Target:
Research Areas:
HSP70 ligand 2 oxooctanoic acid serves as a component of the ligand and linker for Hsp-targeting Chimeras (HspTACs). HSP70 ligand 2 oxooctanoic acid can be used to synthesize Hsp70TAC PD-1 Degrader-2 (HY-182959).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
