24 Results for "

HSP90B

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "HSP90B" in MCE Product Catalog:

4
SNX-2112
SNX-2112
0 Images
4 Cited Publications
Cat. No.: HY-10214
CAS No.: 908112-43-6
Purity:  99.49%
Synonyms: PF-04928473
Target:  

HSP Autophagy

Research Areas:  

Cancer

SNX-2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM for Hsp90 and IC50s of 30 nM, 30 nM for Hsp90 α and Hsp90 β, also induces Her-2 degradation, and inhibits Grp94 and Trap-1, with IC50s of 10 nM, 4.275 μM and 0.862 μM, respectively . SNX-2112 (PF 04928473) binds Hsp90 isoforms Hsp90α, Hsp90β and Hsp90b1/Grp94 with Kds of 4 nM, 6 nM and 484 nM, respectively .
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4
Flavokawain C
Flavokawain C
0 Images
4 Cited Publications
Cat. No.: HY-N2445
CAS No.: 37308-75-1
Category:  

Piperaceae Extract Plants Other Families Extract Flavonoids Chalcones 500 - Internal Server Error | MedChemExpress

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