Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
HSPD1
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "HSPD1" in MCE Product Catalog:
5
2
2 Cited Publications
Research Areas:
KHS101 is a blood-brain barrier-penetrant anticancer agent that primarily functions by inhibiting HSPD1 (IC50 = 14.4 μM) and TACC3 across different cellular backgrounds. KHS101 promotes the aggregation of HSPD1 with client proteins, destabilizes TACC3, and reduces the levels of TACC3, Aurora A and PLK1. KHS101 induces autophagy, apoptosis, cell cycle exit and neuronal differentiation; it suppresses cancer cell growth, motility, EMT and stemness; it also impairs mitochondrial bioenergetics and glycolysis in glioblastoma cells. KHS101 can be used in research related to glioblastoma multiforme and breast cancer [1] .
2
2 Cited Publications
Cat. No.: HY-P73917
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSPD1; HuCHA60; Prev. SPG13; CPN60; HSP60; Spastic Paraplegia 13 (Autosomal Dominant); 60 KDa Heat Shock Protein, Mitochondrial; Epididymis Secretory Sperm Binding Protein; Mitochondrial Matrix Protein P1; Heat Shock 60kD Protein 1 (Chaperonin); 60 KDa Ch
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P73916
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: HSPD1; HuCHA60; Prev. SPG13; CPN60; HSP60; Spastic Paraplegia 13 (Autosomal Dominant); 60 KDa Heat Shock Protein, Mitochondrial; Epididymis Secretory Sperm Binding Protein; Mitochondrial Matrix Protein P1; Heat Shock 60kD Protein 1 (Chaperonin); 60 KDa Chaperonin; Heat Shock 60kDa Protein 1 Isoform 2; Chaperonin 60; Heat Shock 60kDa Protein 1 Isoform 4; GroEL; Short Heat Shock Protein 60 Hsp60s1; Heat Shock 60kDa Protein 1 (Chaperonin); Heat Shock Protein 65; Heat Shock Protein Family D Member 1; HSP65; P60 Lymphocyte Protein; Hsp60; Heat Shock Protein 60; HLD4; Heat Shock Protein Family D (Hsp60) Member 1; HSP-60
Species:
Mouse
Source:
E. coli
Cat. No.: HY-RS18520
Target:
Research Areas:
Hspd1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hspd1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS06447
Target:
Research Areas:
HSPD1 Human Pre-designed siRNA Set A contains three designed siRNAs for HSPD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25002
Target:
Research Areas:
Hspd1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Hspd1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-10996
CAS No.: 1262770-73-9
Research Areas:
KHS101 is a blood-brain barrier-penetrant anticancer agent that primarily functions by inhibiting HSPD1 (IC50 = 14.4 μM) and TACC3 across different cellular backgrounds. KHS101 promotes the aggregation of HSPD1 with client proteins, destabilizes TACC3, and reduces the levels of TACC3, Aurora A and PLK1. KHS101 induces autophagy, apoptosis, cell cycle exit and neuronal differentiation; it suppresses cancer cell growth, motility, EMT and stemness; it also impairs mitochondrial bioenergetics and glycolysis in glioblastoma cells. KHS101 can be used in research related to glioblastoma multiforme and breast cancer [1] .
Cat. No.: HY-N0890R
CAS No.: 102040-03-9
Synonyms: Tubeimoside-1 (Standard); Lobatoside-H (Standard)
Category:
Triterpenes Terpenoids Cucurbitaceae Extract Plants Bolbostemma paniculaum (Maxim)Franguet
Target:
Cat. No.: HY-P73916A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSPD1; HuCHA60; Prev. SPG13; CPN60; HSP60; Spastic Paraplegia 13 (Autosomal Dominant); 60 KDa Heat Shock Protein, Mitochondrial; Epididymis Secretory Sperm Binding Protein; Mitochondrial Matrix Protein P1; Heat Shock 60kD Protein 1 (Chaperonin); 60 KDa Ch
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P86546
Synonyms: HSPD1; HSP60; 60 kDa heat shock protein; mitochondrial; 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; HSP-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein
Cat. No.: HY-P80711A
Synonyms: HSPD1; HSP60; 60 kDa heat shock protein; mitochondrial; 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; HSP-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
