Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
193 Results for "
HUVEC layers
" in MedChemExpress (MCE) Product Catalog:
Products (193)
193 Results for "HUVEC layers" in MCE Product Catalog:
17
17 Publications Verification
Target:
Research Areas:
Dooku1 is a reversibly Yoda1 antagonist with IC50 value of 1.3 μM and 1.5 μM for 2 μM Yoda1-induced Ca 2+ entry HEK 293 cells and HUVECs, respectively. Dooku1 can disrupt Yoda1-induced Piezo1 channel activity and inhibit Yoda1-induced relaxation of aorta. Dooku1 can be used for vascular physiology and disease research .
12
12 Cited Publications
Cat. No.: HY-K3001
DMEM (Dulbecco's Modified Eagle Medium) is a widely used basal medium for supporting the growth of many different mammalian cells. Cell lines successfully cultured in DMEM include Hela, 293, Cos-7, and PC-12, as well as primary fibroblasts, neurons, glial cells, HUVECs, and smooth muscle cells. The 500 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
5
4
4 Cited Publications
Cat. No.: HY-D0155
CAS No.: 288574-78-7
3
Target:
Research Areas:
3
3 Cited Publications
Synonyms: S1P1 agonist 3
Target:
Research Areas:
SAR247799 (S1P1 agonist 3) is an oral activity, selective G-protein-biased sphingosine-1 phosphate receptor-1 (S1P1 ) agonist, with EC50s rang from 12.6 to 493 nM in S1P1-overexpressing cells and HUVECs. SAR247799 can be used for the research of endothelial protection, including type-2 diabetes, metabolic syndrome .
3
3 Cited Publications
Synonyms: L-Ascorbic acid 6-hexadecanoate; 6-O-Palmitoyl-L-ascorbic acid
3
Category:
Infection Plant Ketones, Aldehydes, Acids Metabolic Disease Pinaceae Extract Colophony Extract Disease Research Fields Inflammation/Immunology
Target:
2
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Disease markers Endocrine diseases Microorganism Endogenous metabolite Disease Research Fields Cancer
Target:
2
2 Cited Publications
Cat. No.: HY-N0515
CAS No.: 945619-74-9
1
1 Cited Publications
Cat. No.: HY-W009749
CAS No.: 56-88-2
Category:
Cardiovascular Disease Human Gut Microbiota Metabolites Disease markers Endocrine diseases Amino acids Nervous System Disorder Microorganism Endogenous metabolite Disease Research Fields
Target:
1
1
1 Cited Publications
Cat. No.: HY-W050000
CAS No.: 101328-85-2
Research Areas:
OR-1855, an active metabolite of Levosimendan (HY-14286), has effect on myometrial contractility. OR-1855 exerts anti-inflammatory effects by inhibiting IL-1β-induced ROS formation and NAD(P)H oxidase-dependent superoxide radical generation in HUVECs. OR-1855 inhibits IL-1β-induced phosphorylation p38 MAPK, ERK1/2, c-Jun and JNK in HUVECs. OR-1855 can be used for the study of inflammation .
1
1 Cited Publications
Cat. No.: HY-W229874
CAS No.: 757192-67-9
Research Areas:
EN106 is a potent inhibitor of FEMIB. EN106 is a cysteine-reactive covalent ligand. EN106 disrupts recognition of the key reductive stress substrate of FEM1B, FNIP1. EN106 reduces oxidative stress and rescues high glucose-induced impaired angiogenesis in HUVECs .
1
1 Cited Publications
Cat. No.: HY-W009749C
CAS No.: 61125-50-6
Target:
1
1 Cited Publications
LYG-202, a flavonoid, has potent anti-angiogenic and antitumor activity. LYG-202 inhibits VEGF-stimulated HUVEC migration and tube formation. LYG-202 induces cancer cell apoptosis .
1
1 Cited Publications
Cat. No.: HY-P3418
CAS No.: 891861-48-6
Research Areas:
1
1 Cited Publications
Target:
Research Areas:
PHA-408 is a highly selective, orally active and ATP-competitive IKK-2 inhibitor with an IC50 of 40 nM. PHA-408 blocks NF-κB signaling by suppressing IκBα phosphorylation and degradation, p65 phosphorylation, and pro-inflammatory cytokine production, and prevents TNF-α-induced premature senescence in HUVECs. PHA-408 alleviates LPS-and cigarette smoke-triggered pulmonary inflammation, reduces LPS-stimulated serum TNF-α release, and ameliorates joint damage in SCW-induced arthritis in rats. PHA-408 is applicable for the research of rheumatoid arthritis, chronic obstructive pulmonary disease (COPD), and Duchenne muscular dystrophy .
1
1 Cited Publications
Cat. No.: HY-P2196A
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-W591424
CAS No.: 92451-01-9
Synonyms: mPEG2000-SC; mPEG2000-Succinimidyl ester
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
