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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
Haemonchus contortus
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "Haemonchus contortus" in MCE Product Catalog:
Cat. No.: HY-125159
CAS No.: 187865-22-1
Synonyms: PF-00520904
Derquantel, a spirocyclic anthelmintic, is a competitive, orally active nicotinic acetylcholine receptor (nAChR) antagonist. Derquantel inhibits ACh-induced depolarization with an IC50 of 0.22 μM. By selectively antagonizing nAChRs on the somatic muscles of nematodes, Derquantel causes flaccid paralysis of muscles, thereby dislodging parasites from the host's gastrointestinal tract. Derquantel is applicable to research related to Haemonchus contortus infection and Ascaris suum infection .
Cat. No.: HY-NP0138
Synonyms: PNA (Fluorescein)
Target:
Research Areas:
Peanut Agglutinin (PNA) Fluorescein is a fluorescently labeled lectin that specifically binds to glycosylated cells and Haemonchus contortus. Peanut Agglutinin Fluorescein specifically recognizes and binds to the D-Gal-β(1→3)-D-GalNAc disaccharide sequence and terminal D-galactosyl residues on the cell surface; its binding can be inhibited by D-galactose but is not affected by glucose. Peanut Agglutinin Fluorescein specifically labels cone photoreceptor segments and can also be used to distinguish immature thymocytes from lymphocyte subsets, serving as an effective tool for studying cellular glycosylation status and isolating specific cell populations .
Cat. No.: HY-123686
CAS No.: 71837-27-9
Category:
Target:
Target:
Cat. No.: HY-184373
CAS No.: 1340790-22-8
Synonyms: SN639
SN00799639 (SN639) is an inhibitor of Haemonchus contortus. SN00799639 inhibits the motility of exsheathed third-stage larvae of Haemonchus contortus with an IC50 of 8.4 μM. SN00799639 inhibits the development of exsheathed third-stage larvae of Haemonchus contortus into fourth-stage larvae with an IC50 of 0.29 μM. SN00799639 shows no significant cytotoxicity against human mammary epithelial cells. SN00799639 can be used for research on Haemonchus contortus infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
