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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
94 Results for "
Hemolytic activity
" in MedChemExpress (MCE) Product Catalog:
Products (94)
94 Results for "Hemolytic activity" in MCE Product Catalog:
7
7 Publications Verification
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Quinine hydrochloride is an alkaloid extracted from cinchona bark and exhibits oral activity, acting as a potassium channel inhibitor. Quinine hydrochloride modulates the tolerance of red blood cells and presents dose-dependent toxicity and embryonic effects. Quinine hydrochloride is a typical hemolysin that directly lyses red blood cells, with cellular components of red blood cell membranes as its action targets. Quinine hydrochloride disrupts red blood cell membranes and induces hemolysis at high concentrations, while merely weakening the anti-hemolytic capacity of red blood cells at low concentrations. Quinine hydrochloride continuously reduces red blood cell tolerance after in vivo administration, and high doses can also alter blood cell counts. Quinine hydrochloride can be applied to researches related to red blood cell hemolysis, cancer and malaria .
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Danicopan (ACH-4471), a selective and orally active small-molecule factor D inhibitor, shows high binding affinity to human Factor D with Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits alternative pathway of complement (APC) activity, has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS) .
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3 Cited Publications
Cat. No.: HY-N4087
CAS No.: 66663-90-9
Cat. No.: HY-P990091
CAS No.: 2756228-76-7
Synonyms: SAR445088
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Riliprubart (SAR 445088) is a selective anti-C1s humanized IgG4 monoclonal antibody with mutations that enhance its binding to the neonatal Fc receptor. Riliprubart blocks activation of the classical complement pathway, prevents the formation of the C3 convertase C4b2a, and inhibits complement-mediated hemolytic activity. Riliprubart can be used in research related to classical complement-mediated diseases, cold agglutinin disease, and chronic inflammatory demyelinating polyneuropathy. For the isotype control of Riliprubart, refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo .
Cat. No.: HY-N11630
CAS No.: 97134-11-7
Cat. No.: HY-P5557
CAS No.: 1429184-62-2
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Cat. No.: HY-P3914
CAS No.: 157606-25-2
Synonyms: Oct-CA(1-7)M(2-9)
Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia .
Cat. No.: HY-N2297
CAS No.: 95298-47-8
Category:
Infection Triterpenes Plant Terpenoids Rosaceae Extract Disease Research Fields Sanguisorba officinalis Linn. Extract
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Cat. No.: HY-W010155R
CAS No.: 526-55-6
Synonyms: Indole-3-ethanol (Standard)
Cat. No.: HY-W750342
CAS No.: 75238-45-8
Synonyms: Indole-3-ethanol-d4
Cat. No.: HY-P5016A
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Cat. No.: HY-10545
CAS No.: 119567-79-2
Taribavirin is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin, is a ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia .
Cat. No.: HY-N11546
CAS No.: 30994-75-3
Category:
Eleutherococcus sieboldianus Makino Extract Plant Terpenoids Diterpenoids Araliaceae Extract
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Cat. No.: HY-P1768
CAS No.: 149097-03-0
Synonyms: Uru-TK I
Cat. No.: HY-P10508
CAS No.: 2383114-96-1
Cat. No.: HY-P10536
CAS No.: 1802175-40-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
