25 Results for "

Hep-3B

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "Hep-3B" in MCE Product Catalog:

PROTAC PD-1/PD-L1 degrader-1
PROTAC PD-1/PD-L1 degrader-1
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Cat. No.: HY-131183
CAS No.: 2447066-37-5
Purity:  99.52%
Target:  

PROTACs PD-1/PD-L1

Research Areas:  

Inflammation/Immunology

PROTAC PD-1/PD-L1 degrader-1, a PD-1/PD-L1 PROTAC based on Cereblon E3 ligand, inhibits PD-1/PD-L1 interaction with an IC50 of 39.2 nM. PROTAC PD-1/PD-L1 degrader-1 significantly restores the immunity repressed in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells. PROTAC PD-1/PD-L1 degrader-1 moderately reduces the protein levels of PD-L1 in a lysosome-dependent manner .
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PAT-505
PAT-505
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Cat. No.: HY-107781
CAS No.: 1782070-22-7
Purity:  98.84%
Target:  

Phosphodiesterase (PDE)

Research Areas:  

Inflammation/Immunology

PAT-505 is a potent, selective, noncompetitive and orally available autotaxin inhibitor, with an IC50 of 2 nM in Hep3B cells, 9.7 nM in human blood and 62 nM in mouse plasma.
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LEB-03-146
LEB-03-146
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Cat. No.: HY-144999
CAS No.: 2858812-91-4
Purity:  98.08%
Target:  

DUBTACs Wee1

Research Areas:  

Cancer

LEB-03-146 is a WEE1 DUBTAC (deubiquitinase-targeting chimera) linking AZD1775 (Adavosertib) to the OTUB1 recruiter EN523 through a PEG2 linker. LEB-03-146 shows significant WEE1 stabilization in HEP3B hepatoma cancer cells .
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Protoapigenone
Protoapigenone
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Cat. No.: HY-134008
CAS No.: 862884-32-0
Purity:  99.84%
Category:  

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