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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
200 Results for "
Heterocyclic
" in MedChemExpress (MCE) Product Catalog:
Products (200)
200 Results for "Heterocyclic" in MCE Product Catalog:
10
Category:
Infection Antibiotics Microorganism Disease Research Anticancer Disease Research Fields Other Antibiotics
Target:
6
6 Cited Publications
Cat. No.: HY-W007355
CAS No.: 83-34-1
Synonyms: 3-Methylindole; 3-Methyl-1H-indole
3
3 Cited Publications
Cat. No.: HY-W001132
CAS No.: 120-72-9
Category:
Alkaloids Human Gut Microbiota Metabolites Metabolic Disease Microorganism Endogenous metabolite Disease Research Fields Indole Alkaloids
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3
Category:
Neurological Disease Metabolic Disease Other Families Extract Endogenous metabolite Indole Alkaloids Infection Alkaloids Human Gut Microbiota Metabolites Plant Disease Research Fields Endocrinology
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3
3 Cited Publications
Synonyms: Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene
2
Target:
2
2 Cited Publications
Synonyms: 2-Aminothiazole; 2-Thiazolylamine
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Aminothiazole (2-Aminothiazole), a typical heterocyclic amine, is a precursor for the synthesis of biologically active molecules including sulfur agents, biocides, fungicides, antibiotics, dyes and chemical reaction accelerators .
1
1 Cited Publications
Cat. No.: HY-W018800
CAS No.: 491-36-1
1
1
1 Cited Publications
Synonyms: 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) is the most abundant of generation of heterocyclic amines (HCA), resulted in the cooking of meat . DNA damaging and mutagenic activities. PhIP also has oestrogenic activity that could contribute to its tissue specific carcinogenicity .
1
1 Cited Publications
Cat. No.: HY-P1206
CAS No.: 174688-78-9
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Research Areas:
CH 275 is a peptidic somatostatin analog that acts as an agonist of SST1 (IC50 = 30.9 nM, Ki = 52 nM). The IC50 values of CH 275 for sst3, sst4, sst2, and sst5 are 345 nM, >1 μM, >10 μM, and >10 μM, respectively. CH 275 binds to SSTR1 via the IAmp9-Asp137 ion pair interaction and the hydrophobic interaction between the isopropyl group of IAmp9 and Leu107, and reduces the extracellular acidification rate. CH 275 induces weak sst1 internalization, exerts immunosuppressive effects on macrophages, and decreases macrophage viability, MCP-1 expression/secretion, and IL-8 secretion, but does not alter proMMP-9 secretion or IL-8 mRNA levels. CH 275 reduces hippocampal β-amyloid levels and alleviates plaque pathology without inducing hippocampal microglial activation. CH 275 is used in research on Alzheimer's disease, Parkinson's disease, and depression .
Cat. No.: HY-W012634
CAS No.: 95-16-9
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Cat. No.: HY-P10033
CAS No.: 245080-24-4
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Research Areas:
Cat. No.: HY-21179
CAS No.: 27607-77-8
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Research Areas:
Trimethylsilyl trifluoromethylsulfonate is a metal-free catalyst. Trimethylsilyl trifluoromethylsulfonate can be used for the synthesis of biologically active fluorinated heterocyclic compounds .
Synonyms: TPP; Tetraphenylporphine; meso-Tetraphenylporphyrin
Tetraphenylporphyrin (TPP) is a symmetrically substituted porphyrin-based heterocyclic compound and used as a structural block for supramolecular synthesis. Tetraphenylporphyrin derivatives can be used for cancer research .
Cat. No.: HY-W016349
CAS No.: 138-60-3
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Research Areas:
Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid has good coordination ability with noble metal ions. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM.
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Research Areas:
DMF-DMA (N-Dimethoxymethyl-N,N-dimethylamine) is a reagent with both condensation and alkylation functions. DMF-DMA can undergo condensation reactions with active methylene groups or amino groups to generate enamine and imino derivatives, and can also act as an alkylating agent to methylate nitrogen and oxygen atoms in heterocyclic structures. DMF-DMA is widely used in the synthesis of enaminones and dimethylamino imine intermediates, as well as in the construction of heterocyclic backbones such as pyridine, pyrimidine and pyrazole. DMF-DMA can also serve as a polar aprotic co-solvent; although DMF-DMA cannot dissolve cellulose alone, it can form an efficient cellulose dissolution system with diallylimidazolium methoxyacetate .
Category:
Alkaloids Plant Pyrrole Alkaloids Other Diseases Other Families Extract Disease Research Fields
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
