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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Human LNCap
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Human LNCap" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-16079
CAS No.: 1240299-33-5
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AZD3514 is an orally activie and selective androgen receptor (AR) inhibitor. AZD3514 androgen-dependently and -independently inhibits AR signal. AZD351 down-regulates nuclear AR levels in human LNCaP prostate cancer cells in the absence of androgen with an pIC50 value of 5.75. AZD3514 can be used for the research of prostate cancer .
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Serenoa repens Extract Arecaceae/Palmae Extract Endogenous metabolite Human Gut Microbiota Metabolites Plant Ketones, Aldehydes, Acids Animal Microorganism Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-N16066
CAS No.: 81474-59-1
Synonyms: CHNQD-0803
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Cat. No.: HY-118091A
CAS No.: 148905-78-6
Synonyms: LY300502
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Bexlosteride (LY300502) is a benzoquinolinone human type I 5α-reductase inhibitor. Bexlosteride shows metabolic inhibitory, antiproliferative, and antisecretory effects in LNCaP human prostatic adenocarcinoma cell cultures. Bexlosteride can be used for the research of prostatic cancer .
Cat. No.: HY-141830
CAS No.: 2379410-19-0
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SYY-B029-2 is a potent histone acetyltransferase (HAT) inhibitor with an IC50 of 1.4 nM. SYY-B029-2 cell growth of human mantle cell lymphoma (MCL) cell line MAVER-1 and human castration resistant prostate cancer cell line LNCaP clone FGC, with IC50 values of 15 nM and 13 nM, respectively .
Cat. No.: HY-N15449
CAS No.: 33211-22-2
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Cat. No.: HY-126464
CAS No.: 62899-40-5
Synonyms: EoM
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Estromustine (EoM) is the active metabolite of Estramustine phosphate (HY-13627A). Estromustine binds to mutant androgen receptor (m-AR) with EC50 of 2.6 μM in LNCaP, exhibits cytotoxicity in human prostate cells LNCaP with IC50 of 9.73 μM .
Cat. No.: HY-113332R
CAS No.: 544-64-9
Cat. No.: HY-N10265
CAS No.: 360765-75-9
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Cat. No.: HY-176160
Synonyms: Methyl jacarate; SFE 19:3
Jacaric acid methyl ester is a methyl ester form of the conjugated PUFA jacaric acid. Jacaric acid can induce apoptosis selectively in human prostate cancer cells. Jacaric acid induces concentration- and time-dependent LNCaP cell death. Jacaric acid methyl ester can be studied in anticancer research .
Cat. No.: HY-N3816
CAS No.: 35030-38-7
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Cat. No.: HY-W012088
CAS No.: 56219-06-8
Synonyms: Myristoleic acid methyl ester; Methyl myristoleate; cis-9-Tetradecenoate methyl ester
(Z)-Methyl tetradec-9-enoate (Myristoleic acid methyl ester; Methyl myristoleate) is a cytotoxic component extracted from S. repens fruit extract. It induces apoptosis and necrosis in human prostate cancer LNCaP cells. In addition, (Z)-Methyl tetradec-9-enoate found in cheese-making byproducts inhibits Candida albicans germination with a minimum inhibitory concentration (MIC) of 9 μM in vivo.
Cat. No.: HY-151266
CAS No.: 2883447-45-6
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AR antagonist 4 is an orally active androgen receptor (AR) antagonist with a DC50 of 2.84 μM in LNCaP human prostate cancer cells. AR antagonist 4 inhibits dihydrotestosterone-induced AR transcriptional activity, promotes proteasome-dependent AR degradation, and dose-dependently promotes AR-V7 degradation. AR antagonist 4 can be used for the research of metastatic castration-resistant prostate cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
