Synonyms: Hydroxycarbamide-¹⁵N

Hydroxyurea- ¹⁵N (Hydroxycarbamide- ¹⁵N) is the ¹⁵N labeled Hydroxyurea (HY-B0313). Hydroxyurea is a cell apoptosis inducer that inhibit DNA synthesis through inhibition of ribonucleotide reductase. Hydroxyurea shows anti-orthopoxvirus activity.

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17

Octreotide acetate

17 Cited Publications

Cat. No.: HY-17365

CAS No.: 79517-01-4

Synonyms: SMS 201-995 acetate

Target:

Somatostatin Receptor

Research Areas:

Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer

Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.

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2

Didemnin B

2 Cited Publications

Cat. No.: HY-105055

CAS No.: 77327-05-0

Purity: 99.95%

Category:

Natural Products Animals Marine natural products Other marine organisms Disease Research Fields Cancer

Target:

Others

Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .

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β-Amanitin

Cat. No.: HY-125586

CAS No.: 21150-22-1

Purity: ≥96.0%

Target:

DNA/RNA Synthesis ADC Payloads

Research Areas:

Cancer

β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .

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HYNIC-PSMA

Cat. No.: HY-P5290

CAS No.: 2213408-17-2

Target:

Radionuclide-Drug Conjugates (RDCs) PSMA

Research Areas:

Cancer

HYNIC-PSMA is a ligand for molecular imaging of tumors. Hynic-psma consists of two components: HYNIC (6-hydrazinonicotinamide) and PSMA (Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules, such as ¹⁸⁸Re-HYNIC-PSMA. PSMA is a membrane antigen that is specifically expressed on the surface of prostate cancer cells. HYNIC-PSMA can be used in prostate cancer research . HYNIC-PSMA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

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Plipastatin A1

Cat. No.: HY-P10447

CAS No.: 103651-09-8

Synonyms: Fengycin IX; SNA-60-367-3

Target:

Phospholipase Fungal

Research Areas:

Infection

Plipastatin A1 (Fengycin IX; SNA-60-367-3) is a lipopeptide with phospholipase A2 inhibitory activity. Plipastatin A1 inhibits conidial germination of Botrytis cinerea in vitro and reduces the incidence of gray mold on tomato leaves. Plipastatin A1 is applicable to research related to gray mold ^[1][2].

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HYNIC-iPSMA TFA

Cat. No.: HY-P5292A

CAS No.: 2375849-11-7

Target:

Radionuclide-Drug Conjugates (RDCs) PSMA

Research Areas:

Cancer

HYNIC-iPSMA TFA is a PSMA-targeted ligand for tumor molecular imaging, with a K_i value of 3.11 nM. HYNIC-iPSMA TFA consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC serves as a chelating moiety to link radionuclides to the targeting molecule; iPSMA is a specific inhibitor that targets Prostate-Specific Membrane Antigen (PSMA). 68Ga-labeled iPSMA is used for prostate cancer detection via PET imaging, while the further developed ^99mTc-EDDA/HYNIC-iPSMA TFA exhibits excellent specificity and sensitivity. HYNIC-iPSMA TFA can be used for the synthesis and research of radionuclide-conjugated drugs (RDC) .

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N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide

Cat. No.: HY-P4755

CAS No.: 282726-24-3

Target:

Amino Acid Derivatives

Research Areas:

Others

N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide is a polypeptide composed of L-phenyleline and L-leucine bound to aniline groups. N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide can be used to quantitatively determine the N-terminal heme adduct formed upon exposure to propylene oxide (PO) .

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HYNIC-iPSMA

Cat. No.: HY-P5292

CAS No.: 2192215-74-8

Target:

Radionuclide-Drug Conjugates (RDCs) PSMA

Research Areas:

Cancer

HYNIC-iPSMA is a PSMA-targeted ligand for tumor molecular imaging, with a K_i value of 3.11 nM. HYNIC-iPSMA consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC acts as a chelating moiety to link radionuclides to the targeting molecule; iPSMA is a specific inhibitor that targets Prostate-Specific Membrane Antigen (PSMA). 68Ga-labeled iPSMA is used for prostate cancer detection via PET imaging, while the further developed ^99mTc-EDDA/HYNIC-iPSMA TFA exhibits excellent specificity and sensitivity. HYNIC-iPSMA can be used for the synthesis and research of radionuclide-conjugated drugs (RDC) .

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Orfamide A

Cat. No.: HY-P3100

CAS No.: 939960-34-6

Target:

Parasite

Research Areas:

Infection

Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC₅₀ value of 34.5 μg/mL .

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Ternatin

Cat. No.: HY-125357

CAS No.: 148619-41-4

Target:

Inhibitory Antibodies

Research Areas:

Metabolic Disease

Ternatin (compound 2) is a cyclic heptapeptides that can be isolated from mushroom Coliorus versicolor. Ternatin inhibits fat-accumulation with an IC₅₀ of 0.027 μM in 3T3-L1 adipocytes .

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LPPM-8

Cat. No.: HY-158104

Target:

ATF6

Research Areas:

Others

LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .

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Surfactin C2

Cat. No.: HY-P11783

CAS No.: 86711-55-9

Target:

Fungal

Research Areas:

Infection

Surfactin C2 is a lipopeptide produced by Bacillus subtilis A18 with antifungal activity. Surfactin C2 acts against Heterobasidion annosum and Heterobasidion parviporum. Surfactin C2 exerts its activity mainly through membrane‑active effects to disrupt fungal cell structures and inhibit mycelial growth. Surfactin C2 can be used for the research of butt rot and root rot of conifers .

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