1 Result for "

IAV RdRp

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "IAV RdRp" in MCE Product Catalog:

Cat. No.: HY-143494
CAS No.: 2395007-81-3
Target:  

RSV Influenza Virus

Research Areas:  

Infection

RSV/IAV-IN-3 (compound 14'i) is a dual inhibitor of respiratory syncytial virus (RSV) and influenza A virus (IAV) with EC50 values of 2.92 µM and 1.90 µM,respectively. RSV/IAV-IN-3 has antiviral effect against H1N1 and H3N2 with EC50 values of 3.25 µM and 1.50 µM in MDCK cells, respectively. RSV/IAV-IN-3 significantly inhibits the activity of luciferase in a dose-dependent manner, with an EC50 of 3.89 µM. RSV/IAV-IN-3 inhibits IAV infectivity and RdRp activity. RSV/IAV-IN-3 inhibits IAV and RSV replication at the post-entry stage .
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