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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
IBV
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "IBV" in MCE Product Catalog:
Target:
Research Areas:
Mpro inhibitor N3 is a potent SARS-CoV-2 MPro inhibitor with an EC50 value of 16.77 µM. Mpro inhibitor N3 shows antiviral activities against HCoV-229E, FIPV, IBV and MHV-A59 .
Cat. No.: HY-187507
Target:
Research Areas:
AVI8122 is a covalent coronavirus main protease (M pro) inhibitor, with IC50 values of 0.0047 μM, 0.065 μM, 0.04 μM, 0.004 μM, 0.027 μM and 0.020 μM against SARS-CoV-2, MERS-CoV, HKU8, PEDV, IBV and HKU15, respectively; it exhibits Ki values of 0.14 nM, 1.8 nM, 0.9 nM, 0.2 nM and 5.2 nM against SARS-CoV-2, HKU8, PEDV, IBV and HKU15, respectively. AVI8122 forms a covalent hemithioacetal bond with the catalytic cysteine of M pro, blocks its proteolytic activity, and acts on the four coronavirus genera α, β, γ and δ. AVI8122 is applicable to research related to SARS-CoV-2 infection .\n
Cat. No.: HY-P703548
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1a; pp1a; ORF1a polyprotein; Non-structural protein 2 (nsp2); p87; Papain-like protease nsp3 (PL-PRO) (EC:3.2.2.-, EC:3.4.19.12, EC:3.4.22.-); Non-structural protein 3 (nsp3) ; p195; Non-structural protein 4 (nsp4); Peptide HD2, p41;
Species:
Virus
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
