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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
ICS/LABA
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "ICS/LABA" in MCE Product Catalog:
5
Target:
Research Areas:
Tropisetron Hydrochloride (SDZ-ICS-930) is an effective neuroprotective agent that acts as a 5-HT3 receptor antagonist, a calmodulin inhibitor, and an α7-nAChRreceptor agonist, with an IC50 of 70.1 nM for the 5-HT3 receptor. Tropisetron Hydrochloride has anti-inflammatory properties and immune-regulating functions, effectively alleviating symptoms associated with chemotherapy and post-surgery. Tropisetron Hydrochloride reduces Ab (HY-P4867)-induced hippocampal neuroinflammation .
5
Research Areas:
Tropisetron is an orally active 5-HT3R antagonist (Ki = 5.3 nM) as well as being a potent and selective α7 nicotinic partial agonist (EC50 = 1.3 μM). Tropisetron prevents phosphorylation and activation of the p38 MAPK. Tropisetron inhibits both IL-2 gene transcription and IL-2 synthesis in stimulated T cells. Tropisetron inhibits the binding to DNA and the transcriptional activity of NFAT and AP-1. Tropisetron is anti-inflammatory and antiemetic. Tropisetron has antitumor and neuroprotective effects. Tropisetron can be studied in research for diseases including hemorrhagic cystitis, chronic joint inflammation, lung cancer and chronic cerebral hypoperfusion .
1
1 Cited Publications
Cat. No.: HY-17501A
CAS No.: 81732-46-9
Synonyms: (±)-Bambuterol hydrochloride; KWD-2183 hydrochloride
Target:
Research Areas:
Bambuterol hydrochloride ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a proagent of terbutaline.
Cat. No.: HY-111144
CAS No.: 915133-65-2
Synonyms: AZD0548; LAS100977
Target:
Research Areas:
Abediterol (LAS100977) is an inhaled long-acting β2-adrenoceptor agonist (LABA) and can be used for the research of asthma and chronic obstructive pulmonary disease (COPD) .
Cat. No.: HY-17501S
CAS No.: 1794810-59-5
Synonyms: (±)-Bambuterol-d9 hydrochloride; KWD-2183-d9 hydrochloride
Cat. No.: HY-17501
CAS No.: 81732-65-2
Synonyms: (±)-Bambuterol; KWD-2183
Category:
Target:
Cat. No.: HY-B0072S
CAS No.: 1220284-86-5
Synonyms: SDZ-ICS-930-d5 free base
Cat. No.: HY-B0020R
CAS No.: 105826-92-4
Synonyms: SDZ-ICS-930 (Standard)
Target:
Research Areas:
Tropisetron (Hydrochloride) (Standard) is the analytical standard of Tropisetron (Hydrochloride). Tropisetron Hydrochloride (SDZ-ICS-930) is an effective neuroprotective agent that acts as a 5-HT3 receptor antagonist, a calmodulin inhibitor, and an α7-nAChRreceptor agonist, with an IC50 of 70.1 nM for the 5-HT3 receptor. Tropisetron Hydrochloride has anti-inflammatory properties and immune-regulating functions, effectively alleviating symptoms associated with chemotherapy and post-surgery. Tropisetron Hydrochloride reduces Ab (HY-P4867)-induced hippocampal neuroinflammation .
Cat. No.: HY-117024
CAS No.: 1044516-17-7
Synonyms: AZD0548 napadisylate; LAS100977 napadisylate
Target:
Research Areas:
Abediterol napadisylate is an inhaled long-acting β2-adrenoceptor agonist (LABA) and can be used for the research of asthma and chronic obstructive pulmonary disease (COPD) .
Cat. No.: HY-17501AR
CAS No.: 81732-46-9
Synonyms: (±)-Bambuterol hydrochloride (Standard); KWD-2183 hydrochloride (Standard)
Research Areas:
Bambuterol hydrochloride (Standard) is the analytical standard of Bambuterol hydrochloride. This product is intended for research and analytical applications. Bambuterol hydrochloride ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a proagent of terbutaline.
Cat. No.: HY-14299C
CAS No.: 1000160-97-3
Target:
Research Areas:
Indacaterol xinafoate is an orally active long-acting β2-adrenergic agonist (LABA) with bronchodilatory effect. Indacaterol inhibits NF-κB activity in a β-arrestin2-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol xinafoate can be utilized in asthma research .
Cat. No.: HY-128557
CAS No.: 1323941-49-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
