954 Results for "

Il6

" in MedChemExpress (MCE) Product Catalog:

Products (954)

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550

Resatorvid

550 Publications Verification

Cat. No.: HY-11109

CAS No.: 243984-11-4

Purity: 98.92%

Synonyms: TAK-242; CLI-095

Target:

Toll-like Receptor (TLR) TNF Receptor Interleukin Related Autophagy

Research Areas:

Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. Resatorvid inhibits NO, TNF-α and IL-6 production with IC_50s of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy and plays pivotal role in various inflammatory diseases .

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126

Resiquimod

126 Cited Publications

Cat. No.: HY-13740

CAS No.: 144875-48-9

Purity: 99.87%

Synonyms: R848; S28463

Target:

Toll-like Receptor (TLR) HCV

Research Areas:

Inflammation/Immunology Cancer

Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α.

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IL-6 Protein, Human

63 Cited Publications

Cat. No.: HY-P7044

Purity: ≥ 95%, as determined by reducing SDS-PAGE.

Synonyms: Il6; Hybridoma Growth Factor; Prev. IFNB2; IFN-Beta-2; Il-6; BSF-2; Interleukin-6; CDF; BSF2; Interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated Interleukin 6; B-Cell Stimulatory Factor 2; Interferon, Beta 2; CTL Differ

Species:

Human

Source:

E. coli

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Tocilizumab

51 Cited Publications

Cat. No.: HY-P9917

CAS No.: 375823-41-9

Synonyms: Anti-Human Il6R, Humanized Antibody; RG-1569; rhPM-1

Tocilizumab (Anti-Human IL6R, Humanized Antibody) is an anti-human interleukin-6 receptor (IL-6R) neutralizing antibody, prevents binding of IL-6 to the IL-6R, thereby inhibiting both classic and trans-signaling. Tocilizumab (Anti-Human IL6R, Humanized Antibody) can be used for the treatment of rheumatoid arthritis . Tocilizumab is remarkablely effective for the study of severe COVID-19 (coronavirus disease) .

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IL-6 Protein, Mouse

34 Cited Publications

Cat. No.: HY-P7063

Purity: ≥ 95%, as determined by reducing SDS-PAGE.

Species:

Mouse

Source:

E. coli

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Methylprednisolone

21 Cited Publications

Cat. No.: HY-B0260

CAS No.: 83-43-2

Synonyms: U 7532

Target:

Glucocorticoid Receptor Autophagy SARS-CoV Bacterial

Research Areas:

Cardiovascular Disease Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Methylprednisolone (U 7532) is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels .

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