84 Results for "

Infarct

" in MedChemExpress (MCE) Product Catalog:
Products (84)

84 Results for "Infarct" in MCE Product Catalog:

59
Raleukin
Raleukin
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59 Publications Verification
Cat. No.: HY-108841
CAS No.: 143090-92-0
Purity:  99.40%
Synonyms: Kineret; Anakinra

Target:  

Interleukin Related

Research Areas:  

Infection Inflammation/Immunology Cancer

Raleukin (Kineret) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Raleukin significantly reduces neutrophil accumulation in blood vessels and brain infarct volume as well as improves motor coordination performance in ischemic stroke mice model. Anakinra can be used to study chronic inflammatory disorders like rheumatoid arthritis and cardiovascular recurrence post-myocardial infarction .
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14
Sulfaphenazole
Sulfaphenazole
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14 Cited Publications
Cat. No.: HY-B1218
CAS No.: 526-08-9
Target:  

Cytochrome P450 Antibiotic Bacterial Necroptosis Apoptosis

Research Areas:  

Infection Cardiovascular Disease

Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion .
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12
ATN-161
ATN-161
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12 Cited Publications
Cat. No.: HY-13535
CAS No.: 262438-43-7
Target:  

Integrin Apoptosis NOD-like Receptor (NLR) p38 MAPK Reactive Oxygen Species (ROS) SARS-CoV

Research Areas:  

Cardiovascular Disease Infection Neurological Disease Cancer

ATN-161 is an antagonist of α5β1 integrin and αvβ3 integrin, as well as an inhibitor of fibrosis, an inhibitor of oxidative stress, a tight junction stabilizer, a mitochondrial integrity protector, an angiogenesis inhibitor and an antiviral agent. ATN-161 inhibits NLRP3, MAPK, and ROS. ATN-161 protects mice from SARS-CoV-2 infection . ATN-161 reduces infarct volume, alleviates edema, decreases immune cell infiltration, reduces the area of choroidal neovascularization lesions, lowers tumor microvessel density and viral load. ATN-161 can be used in research related to ischemic stroke, choroidal neovascularization, breast cancer, coronavirus disease 2019 (COVID-19), and liver metastasis of colorectal cancer .
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11
Ligustrazine
Ligustrazine
0 Images
11 Cited Publications
Cat. No.: HY-N0264
CAS No.: 1124-11-4
Synonyms: Chuanxiongzine; Tetramethylpyrazine
Category:  

Cardiovascular Disease Natural Products Neurological Disease 500 - Internal Server Error | MedChemExpress

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