14 Results for "

J774a.1

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "J774a.1" in MCE Product Catalog:

Oxalomalic acid trisodium
Oxalomalic acid trisodium
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Cat. No.: HY-131521
CAS No.: 89304-26-7
Synonyms: Oxalomalate trisodium
Target:  

Isocitrate Dehydrogenase (IDH)

Research Areas:  

Cancer

Oxalomalic acid (Oxalomalate) trisodium is a aconitase and NADP-dependent isocitrate dehydrogenase inhibitor. Oxalomalic acid trisodium inhibits nitrite production and iNOS protein expression in lipopolysaccharide (HY-D1056)-activated J774 macrophages .
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JC-171
JC-171
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Cat. No.: HY-117432
CAS No.: 2112809-98-8
Purity:  98.41%
Target:  

NOD-like Receptor (NLR)

Research Areas:  

Inflammation/Immunology

JC-171 is a selective NLRP3 inflammasome inhibitor, with an IC50 of 8.45 μM for inhibiting LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages .
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TAN-1030A
TAN-1030A
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Cat. No.: HY-N16039
CAS No.: 126221-76-9
Category:  

Alkaloids Microorganisms Indole Alkaloids

Target:  

β-glucuronidase

TAN-1030A is an indolocarbazole alkaloid with macrophage-activating properties. TAN-1030A induces spreading of a murine macrophage cell line, Mm 1, and augmentes the phagocytic activity, Fc gamma receptor expression and β-glucuronidase activity of murine macrophage cell lines, Mm 1 and J774A.1. TAN-1030A can activate macrophage functions in mice .
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IIIM-1270
IIIM-1270
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Cat. No.: HY-133133
CAS No.: 4818-19-3
Target:  

NOD-like Receptor (NLR) Interleukin Related

Research Areas:  

Inflammation/Immunology

IIIM-1270is a NLRP3 inflammasome inhibitor. IIIM-1270 inhibits IL-1β release in mouse macrophages (J774A.1 cells) (IC50 = 3.5 μM) and significantly reduced the protein expression level of mature IL-1β. IIIM-1270 can be used for the study of inflammation .
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N-Sterol
N-Sterol
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Cat. No.: HY-171905
CAS No.: 3069417-18-8
Target:  

Liposome

Research Areas:  

Others

N-Sterol is a sterol lipid that has been used to generate lipid nanoparticles (LNPs) for delivery of mRNA in vitro and in vivo. N-Sterol LNPs are taken up in J774A.1 macrophages in a lipid composition-dependent manner via clathrin caveolae, caveolin-mediated endocytosis, micropinocytosis, or phagocytosis at different frequencies .
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Apiin (Standard)
Apiin (Standard)
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Cat. No.: HY-N0577R
CAS No.: 26544-34-3
Synonyms: Apigenin 7-O-apiosylglucoside (Standard); Apigenin 7-(2-O-apiosylglucoside) (Standard)
Category:  

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