2 Results for "

JIMT-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "JIMT-1" in MCE Product Catalog:

VLS-1272
VLS-1272
0 Images
Cat. No.: HY-153066
CAS No.: 2914878-00-3
Purity:  98.09%
Synonyms: KIF18A-IN-7
Target:  

Kinesin Microtubule/Tubulin Apoptosis

Research Areas:  

Cancer

VLS-1272 (Compound 22) is an orally active KIF18A inhibitor that binds to the KIF18A-microtubule complex in an ATP-noncompetitive manner (IC50 = 41 nM), blocking its ATPase activity and inhibiting microtubule translocation. This leads to abnormal accumulation of KIF18A at spindle poles, disrupting chromosome alignment and inducing mitotic arrest and apoptosis in CIN High tumor cells (e.g., ovarian cancer OVCAR-3, breast cancer JIMT-1). VLS-1272 is a promising candidate for anti-tumor research [1] .
loading...
    loading...
View All Sizes
Sideritoflavone
Sideritoflavone
0 Images
Cat. No.: HY-N1305
CAS No.: 70360-12-2
Synonyms: Sideritiflavone
Category:  

Flavonoids Flavones 500 - Internal Server Error | MedChemExpress

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.