Purity: 97.25%

Synonyms: KAR5585

Target:

Research Areas:

Rodatristat ethyl (KAR5585) is a first-in-class oral tryptophan hydroxylase 1 (TPH1) Inhibitor with nanomolar in vitro potency. Rodatristat ethyl reduces the level of 5-HT and significantly reduces pulmonary arterial hypertension (PAH) .

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BPAM344

Cat. No.: HY-129086

CAS No.: 1204572-55-3

Purity: 99.66%

Target:

iGluR

Research Areas:

Neurological Disease

BPAM344 is a kainate receptor (KAR) subunits GluK1b, GluK2a, and GluK3a positive allosteric modulator (PAM) .

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Rodatristat

Cat. No.: HY-120083

CAS No.: 1673568-73-4

Purity: 99.11%

Synonyms: KAR5417

Target:

5-HT Receptor Tryptophan Hydroxylase

Research Areas:

Cardiovascular Disease

Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC₅₀s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice .

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KK181N1

Cat. No.: HY-168432

Target:

Phytohormone

Research Areas:

Others

KK181N1 is a potent inhibitor of karrikin (KAR) receptor KAI2. KK181N1 binds to the catalytic pockets of KAI2 in a non-covalent binding manner. KK181N1 selectively depress the KAR-induced phenotypes in Arabidopsis .

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HSD17B12 Human Pre-designed siRNA Set A

Cat. No.: HY-RS06392

Target:

Small Interfering RNA (siRNA)

Research Areas:

Others

HSD17B12 Human Pre-designed siRNA Set A contains three designed siRNAs for HSD17B12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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KAR425

Cat. No.: HY-116552

CAS No.: 1809050-49-4

Target:

Parasite

Research Areas:

Infection

KAR425 is a potent and orally active antimalarial agent. KAR425 shows antimalarial activity against the Chloroquine-sensitive (CQS) D6, the Chloroquine-resistant (CQR) Dd2, and 7G8 strains of Plasmodium falciparum, with IC₅₀ values of 62 nM, 55 nM, and 60 nM, respectively .

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KARS1 Human Pre-designed siRNA Set A

Cat. No.: HY-RS07071

Target:

Small Interfering RNA (siRNA)

Research Areas:

Others

KARS1 Human Pre-designed siRNA Set A contains three designed siRNAs for KARS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Rapaprutug

Cat. No.: HY-P991156

CAS No.: 2994192-38-8

Rapaprutug is a monoclonal antibody targeting human KARS1 (lysyl-tRNA synthetase 1). Rapaprutug blocks the relevant inflammatory signaling pathways in which KARS1 is involved, reducing the production and release of inflammatory factors. Rapaprutug is promising for research of inflammatory diseases .

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