2 Results for "

KBV cells

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "KBV cells" in MCE Product Catalog:

Antitumor agent-200
Antitumor agent-200
0 Images
Cat. No.: HY-173182
CAS No.: 3046118-64-0
Target:  

Microtubule/Tubulin P-glycoprotein

Research Areas:  

Cancer

Antitumor agent-200 (Compound 2g) is a microtubule synthesis inhibitor. By binding to the colchicine site of tubulin, it causes G2/M cell cycle arrest and generates reactive oxygen species (ROS). Antitumor agent-200 exhibits significant inhibitory activity against MCF7/ADR and KBV200 cell lines with overexpression of P-glycoprotein (P-gp), with drug resistance indices (DRI) of 0.83 and 0.58 respectively. In the MCF-7 xenograft model, Antitumor agent-200 (25 mg/kg, intraperitoneal injection) can achieve a tumor growth inhibition rate of 57.2%. Antitumor agent-200 can be used in the research of the anti-cancer field .
loading...
    loading...
View All Sizes
10S,13aR-Antofine N-oxide
10S,13aR-Antofine N-oxide
0 Images
Cat. No.: HY-N17304
CAS No.: 314744-17-7
Category:  

Alkaloids Other Alkaloids Plants 500 - Internal Server Error | MedChemExpress

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.