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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
KCa1.1
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "KCa1.1" in MCE Product Catalog:
6
6 Publications Verification
Target:
Research Areas:
GAL-021 is a potent BKCa-channel blocker. GAL-021 inhibits KCa1.1 in GH3 cells. GAL-021 is a novel breathing control modulator that is based on selective modification of the almitrine pharmacophore. GAL-021 increases minute ventilation in rats and non-human primates .
3
3 Cited Publications
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NS 11021 is a potent and specific Ca 2+-activated big-conductance K + Channels (KCa1.1 channels) activator. NS 11021 at concentrations above 0.3 μM activates KCa1.1 in a concentration-dependent manner by parallelshifting the channel activation curves to more negative potentials .
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NS19504 is a Ca 2+-activated K + channel (BK channel, KCa1.1 channel) activator (EC50=11.0 μM) with relaxing effect on bladder smooth muscle spontaneous phasic contractions .
Cat. No.: HY-146174
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Research Areas:
KCa1.1 channel activator-2 (compound 3F), a Quercetin hybrid derivative, is a selective vascular KCa1.1 channel stimulator. KCa1.1 channel activator-2 exhibits potent myorelaxant activity .
Cat. No.: HY-146173
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Research Areas:
KCa1.1 channel activator-1 (compound 1E), a Quercetin hybrid derivative, is a selective vascular KCa1.1 channel channel stimulator. KCa1.1 channel activator-1 also displays CaV1.2 channel blocking activity. KCa1.1 channel activator-1 exhibits weak myorelaxant activity .
Cat. No.: HY-101422A
CAS No.: 1380342-00-6
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GAL-021 sulfate is a potent BKCa-channel blocker. GAL-021 sulfate inhibits KCa1.1 in GH3 cells. GAL-021 sulfate is a novel breathing control modulator that is based on selective modification of the almitrine pharmacophore. GAL-021 sulfate increases minute ventilation in rats and non-human primates .
Cat. No.: HY-RS20560
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Research Areas:
Kcnma1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kcnma1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27069
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Research Areas:
Kcnma1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Kcnma1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07164
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KCNMA1 Human Pre-designed siRNA Set A contains three designed siRNAs for KCNMA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-110153R
CAS No.: 327062-46-4
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NS19504 (Standard) is the analytical standard of NS19504 (HY-110153). This product is intended for research and analytical applications. NS19504 is a Ca2+-activated K+ channel (BK channel, KCa1.1 channel) activator (EC50=11.0 μM) with relaxing effect on bladder smooth muscle spontaneous phasic contractions .
Cat. No.: HY-101422R
CAS No.: 1380341-99-0
Target:
Research Areas:
GAL-021 (Standard) is the analytical standard of GAL-021 (HY-101422). This product is intended for research and analytical applications. GAL-021 is a potent BKCa-channel blocker. GAL-021 inhibits KCa1.1 in GH3 cells. GAL-021 is a novel breathing control modulator that is based on selective modification of the almitrine pharmacophore. GAL-021 increases minute ventilation in rats and non-human primates .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
