1 Result for "

KU14R

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KU14R" in MCE Product Catalog:

Cat. No.: HY-15481
CAS No.: 189224-48-4
Purity:  98.91%
KU14R, an imidazole analog of efaroxan, is a putative imidazoline I3 receptor antagonist and reversible KATP channel inhibitor. KU14R inhibits KATP channel activity in mouse pancreatic β cells with an IC50 of 31.9 μmol/L, and also suppresses Kir6.2 ΔC26 channel activity. KU14R exerts model-dependent antagonistic effects on imidazoline-sensitive insulin secretion. KU14R can be used in the research of diabetes-related diseases .
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