1839 Results for "

L57F TNF

" in MedChemExpress (MCE) Product Catalog:
Products (1839)

1839 Results for "L57F TNF" in MCE Product Catalog:

550
Resatorvid
Resatorvid
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550 Publications Verification
Cat. No.: HY-11109
CAS No.: 243984-11-4
Purity:  98.92%
Synonyms: TAK-242; CLI-095
Target:  

Toll-like Receptor (TLR) TNF Receptor Interleukin Related Autophagy

Research Areas:  

Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. Resatorvid inhibits NO, TNF-α and IL-6 production with IC50s of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy and plays pivotal role in various inflammatory diseases .
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530
BAY 11-7082
BAY 11-7082
0 Images
530 Cited Publications
Cat. No.: HY-13453
CAS No.: 19542-67-7
Purity:  99.98%
Synonyms: BAY 11-7821
Target:  

IKK Deubiquitinase Autophagy Apoptosis NF-κB

Research Areas:  

Inflammation/Immunology Cancer

BAY 11-7082 is an IκBα phosphorylation and NF-κB inhibitor. BAY 11-7082 selectively and irreversibly inhibits the TNF-α-induced phosphorylation of IκB-α, and decreases NF-κB and expression of adhesion molecules. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 (IC50=0.19, 0.96 μM, respectively). BAY 11-7082 inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells .
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126
Resiquimod
Resiquimod
0 Images
126 Cited Publications
Cat. No.: HY-13740
CAS No.: 144875-48-9
Purity:  99.87%
Synonyms: R848; S28463
Target:  

Toll-like Receptor (TLR) HCV

Research Areas:  

Inflammation/Immunology Cancer

Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α.
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78
TNF-alpha/TNFSF2 Protein, Human
TNF-alpha/TNFSF2 Protein, Human
0 Images
78 Cited Publications
Cat. No.: HY-P7058
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNF; Tumor Necrosis Factor (TNF Superfamily, Member 2); Prev. TNFA; Tumor Necrosis Factor-Alpha; TNF-Alpha; Tumor Necrotic Factor Alpha; TNFSF2; TNF Superfamily, Member 2; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF, Macrophage-Derived; TNF-A; TNF, Monocyte-Derived; DIF; APC1 Protein; Cachectin; IMD127; TNLG1F; Tumor Necrosis Factor; Tumor Necrosis Factor Ligand 1F
Species:  
Human
Source:  
E. coli
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76
Shikonin
Shikonin
0 Images
76 Cited Publications
Cat. No.: HY-N0822
CAS No.: 517-89-5
Synonyms: C.I. 75535; Isoarnebin 4
Category:  

Quinones Boraginaceae Extract Plants 500 - Internal Server Error | MedChemExpress

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