13 Results for "

LacCer

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "LacCer" in MCE Product Catalog:

Cat. No.: HY-153830
CAS No.: 4201-62-1
Synonyms: C16 Lactosylceramide (d18:1/16:0)
LacCer (d18:1/16:0) (C16 Lactosylceramide (d18:1/16:0)) is an endogenous bioactive sphingolipid that can form membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs). The levels of LacCer (d18:1/16:0) are elevated in the plasma of insulin-resistant cattle. In a mouse model of Niemann-Pick type C1 disease (a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder), the expression of LacCer (d18:1/16:0) is also upregulated. LacCer (d18:1/16:0) can be used in research on metabolic diseases and neurodegenerative diseases .
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Cat. No.: HY-154921
CAS No.: 4682-48-8
Purity:  ≥98.0%
Synonyms: LacCer (bovine buttermilk)
Target:  

Endogenous Metabolite

Research Areas:  

Others

Lactosylceramide (bovine buttermilk) (LacCer (bovine buttermilk)) is a natural lactosylceramide (LacCer) mixture derived from bovine buttermilk, belonging to neutral glycosphingolipids, and composed of a lactose polar head group and a ceramide backbone. LacCer is an important component of cell membrane glycosphingolipids and is associated with processes such as signal transduction, cell recognition, cell adhesion, and cell growth. LacCer derived from bovine buttermilk contains multiple molecular species composed of different long-chain bases and fatty acyl groups. Lactosylceramide (bovine buttermilk) can be used for research related to lactosylceramide and glycosphingolipids .
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Cat. No.: HY-N15932
CAS No.: 2260670-19-5
Category:  

Lipids

C6(6-Azido) LacCer is a clickable sphingolipid.
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Cat. No.: HY-153830S
CAS No.: 2097249-92-6
Synonyms: C16 Lactosylceramide (d18:1/16:0)-d3
LacCer (d18:1/16:0) (C16 Lactosylceramide (d18:1/16:0))-d3 is the deuterium labeled LacCer (d18:1/16:0) (HY-153830). LacCer (d18:1/16:0) is an endogenous bioactive sphingolipid that can form membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs). LacCer (d18:1/16:0) are elevated in the plasma of insulin-resistant cattle. LacCer (d18:1/16:0) is also upregulated in a mouse model of Niemann-Pick type C1 disease (a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder). LacCer (d18:1/16:0) can be used in research on metabolic diseases and neurodegenerative diseases .
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Cat. No.: HY-N17233
CAS No.: 105087-85-2
LacCer(d18:1/24:0) is a lipid. LacCer(d18:1/24:0) can be found in plasma. LacCer(d18:1/24:0) is associated with critical illness after cardiac surgery .
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Cat. No.: HY-154921A
Synonyms: LacCer (porcine RBC)
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

Lactosylceramide (LacCer) (porcine RBC) is an endogenous bioactive sphingolipid. Lactosylceramide (porcine RBC) plays a pivotal role in mediating innate immune functions .
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Cat. No.: HY-116392A
CAS No.: 161491-04-9
Research Areas:  

Cancer

(−)-L-threo-PDMP hydrochloride is the hydrochloride form of (−)-L-threo-PDMP. L-threo-PDMP is a glucosylceramide synthase (GCS) inhibitor. L-threo-PDMP stimulates the proliferation of cultured aortic smooth muscle cells, and that increases the level of LacCer in B16 melanoma cells .
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Cat. No.: HY-E70049
CAS No.: 67338-98-1
Synonyms: GM2/GD2 synthase
Target:  

Others

Research Areas:  

Neurological Disease

beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) (GM2/GD2 synthase) is a key enzyme which catalyzes the conversion of GM3, GD3 and lactosylceramide (LacCer) to GM2, GD2 and asialo-GM2 (GA2), respectively. beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) is a key enzyme to control the synthesis of brain-enriched complex gangliosides .
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Cat. No.: HY-153828
CAS No.: 384842-72-2
Target:  

Others

Research Areas:  

Metabolic Disease

LacCer (d18:1/8:0) is a glycosphingolipid.
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Cat. No.: HY-156208
CAS No.: 574738-16-2
Synonyms: AdaGalCer(d18:1/2:0); Admantanyl galactosylceramide (d18:1/2:0); Admantanyl galCer(d18:1/2:0)
C2 Adamantanyl galactosylceramide (AdaGalCer) (d18:1/2:0) is a bioactive sphingolipid. C2 Adamantanyl galactosylceramide (d18:1/2:0) stimulates glucocerebrosidase activity in vitro. C2 Adamantanyl galactosylceramide (d18:1/2:0) inhibits microsomal LacCer and Gb3 synthase, and inhibits cell sulfatide synthesis. C2 Adamantanyl galactosylceramide (d18:1/2:0) reduces glucosylceramide (GlcCer) levels in normal and lysosomal storage disease (LSD) cells. C2 Adamantanyl galactosylceramide (d18:1/2:0) acts as a substrate for A4GALT and is able to lower Gb3 levels with an IC50 concentration of 40 μM in fabry disease cells .
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Cat. No.: HY-153860
CAS No.: 125650-87-5
LacCer (d18:1/20:0) is a lipid whose level is closely associated with atherosclerosis and cardiovascular diseases .
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Cat. No.: HY-153861
CAS No.: 483370-78-1
Synonyms: C24:1 Lactosyl(β) Ceramide (d18:1/24:1)
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

LacCer(d18:1/24:1) is a sphosphingolipid.
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Cat. No.: HY-181469
Synonyms: Adamantanyl GluCer (d18:1/2:0); Adamantanyl glucosylceramide (d18:1/2:0); AdaGluCer (d18:1/2:0)
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

C2 Adamantanyl glucosylceramide (d18:1/2:0) (Adamantanyl GluCer (d18:1/2:0)) is an inhibitor of glucocerebrosidase (GCC) and LacCer synthase. At low doses, C2 Adamantanyl glucosylceramide (d18:1/2:0) increases intracellular glycolipid levels by inhibiting glucocerebrosidase. C2 Adamantanyl glucosylceramide (d18:1/2:0) alters glycolipid metabolism. C2 Adamantanyl glucosylceramide (d18:1/2:0) can be used for the research of Gaucher disease and Fabry disease .
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