7 Results for "

Langerin

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Langerin" in MCE Product Catalog:

Cat. No.: HY-W069974
CAS No.: 79932-56-2
Target:  

Calcium Channel

Research Areas:  

Inflammation/Immunology

Ca2+-Langerin-IN-1 (Compound 3) is a allosteric Langerin inhibitor. Langerin is a C-type lectin that is expressed on Langerhans cells and plays a crucial role in pathogen recognition and innate immune activation. The KD value of the CRD domain of murine Langerin protein for Ca2+-Langerin-IN-1 is 17 μM under the presence of Ca²⁺ and 53 μM under the absence of Ca²⁺ competition. Ca2+-Langerin-IN-1 induces conformational changes and competitively replaces Ca²⁺, thereby inhibiting the carbohydrate recognition function of the protein. Ca2+-Langerin-IN-1 can be used in the research of immunomodulatory therapy .
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Cat. No.: HY-P71602
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD207; Langerhans Cell Specific C-Type Lectin; CD207 Molecule; CD207 Molecule, Langerin; CLEC4K; CD207 Antigen, Langerin; C-Type Lectin Domain Family 4 Member K; C-Type Lectin Domain Family 4, Member K; Langerin; CD207 Antigen
Species:  
Mouse
Source:  
E. coli
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Cat. No.: HY-P7819
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD207; Langerhans Cell Specific C-Type Lectin; CD207 Molecule; CD207 Molecule, Langerin; CLEC4K; CD207 Antigen, Langerin; C-Type Lectin Domain Family 4 Member K; C-Type Lectin Domain Family 4, Member K; Langerin; CD207 Antigen
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P77437
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD207; Langerhans Cell Specific C-Type Lectin; CD207 Molecule; CD207 Molecule, Langerin; CLEC4K; CD207 Antigen, Langerin; C-Type Lectin Domain Family 4 Member K; C-Type Lectin Domain Family 4, Member K; Langerin; CD207 Antigen
Species:  
Rhesus Macaque
Source:  
HEK293
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Cat. No.: HY-P81521A
Synonyms: CD207; CD207 antigen; Langerin; CD207 molecule; CLEC4K; Langerhans cell specific c type lectin; Langerin

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P81521
Synonyms: CD207; CD207 antigen; Langerin; CD207 molecule; CLEC4K; Langerhans cell specific c type lectin; Langerin

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P87979
Synonyms: CD207, CLEC4K, C-type lectin domain family 4 member K, Langerin

Host:  

Rabbit

Application:  

IHC-P, IHC-F, IF-Tissue

Reactivity:  

Human

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