7 Results for "

Lassa fever

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Lassa fever" in MCE Product Catalog:

12
Losmapimod
Losmapimod
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12 Cited Publications
Cat. No.: HY-10402
CAS No.: 585543-15-3
Purity:  99.94%
Synonyms: GSK-AHAB; GW856553X; SB856553
Target:  

p38 MAPK NF-κB Apoptosis Arenavirus

Research Areas:  

Cardiovascular Disease Infection Neurological Disease Cancer

Losmapimod (GSK-AHAB; GW856553X) is an orally active p38α/β MAPK inhibitor, with pKi values of 8.1 and 7.6 for p38α and p38β, respectively. Losmapimod reduces DUX4 expression, thus exerting efficacy in facioscapulohumeral muscular dystrophy. By inhibiting MAPK/NF-κB, Losmapimod reduces apoptosis of epileptiform hippocampal neurons, and exhibits anti-allodynia and anti-hyperalgesic activities. Losmapimod blocks the entry and fusion of Lassa fever virus (LASV). Losmapimod overcomes tyrosine kinase inhibitor resistance in non-small cell lung cancer (NSCLC). Losmapimod inhibits myocardial senescence and inflammation, and possesses cardioprotective activity against cardiotoxicity .
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LASV-IN-1
LASV-IN-1
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Cat. No.: HY-124871
CAS No.: 554438-52-7
Purity:  99.87%
Target:  

Arenavirus

Research Areas:  

Infection

LASV-IN-1 is a Lassa fever virus (LASV) inhibitor. LASV-IN-1 binds with LASV glycoprotein (GP) and promotes virus membrane fusion and infection. LASV-IN-1 can be used for LASV infection research .
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Licoisoflavone B
Licoisoflavone B
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Cat. No.: HY-N3388
CAS No.: 66056-30-2
Category:  

Flavonoids Metabolic Disease Phenols Polyphenols 500 - Internal Server Error | MedChemExpress

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