12 Results for "

Lassa virus

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "Lassa virus" in MCE Product Catalog:

12
Losmapimod
Losmapimod
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12 Publications Verification
Cat. No.: HY-10402
CAS No.: 585543-15-3
Purity:  99.94%
Synonyms: GSK-AHAB; GW856553X; SB856553
Target:  

p38 MAPK NF-κB Apoptosis Arenavirus

Research Areas:  

Cardiovascular Disease Infection Neurological Disease Cancer

Losmapimod (GSK-AHAB; GW856553X) is an orally active p38α/β MAPK inhibitor, with pKi values of 8.1 and 7.6 for p38α and p38β, respectively. Losmapimod reduces DUX4 expression, thus exerting efficacy in facioscapulohumeral muscular dystrophy. By inhibiting MAPK/NF-κB, Losmapimod reduces apoptosis of epileptiform hippocampal neurons, and exhibits anti-allodynia and anti-hyperalgesic activities. Losmapimod blocks the entry and fusion of Lassa fever virus (LASV). Losmapimod overcomes tyrosine kinase inhibitor resistance in non-small cell lung cancer (NSCLC). Losmapimod inhibits myocardial senescence and inflammation, and possesses cardioprotective activity against cardiotoxicity .
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4
LHF-535
LHF-535
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4 Cited Publications
Cat. No.: HY-112762
CAS No.: 1450929-77-7
Purity:  99.14%
Target:  

Arenavirus

Research Areas:  

Infection

LHF-535 is an antiviral agent extracted from patent WO2013123215A2, Compound 38, has EC50s of <1 μM, <1 μM, <1 μM, and 1-10 μM for Lassa, Machupo, Junin, and VSVg virus, respectively .
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4
ST-193
ST-193
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4 Cited Publications
Cat. No.: HY-101441
CAS No.: 489416-12-8
Purity:  99.93%
Target:  

Arenavirus

Research Areas:  

Infection

ST-193 is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively.
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4
ST-193 hydrochloride
ST-193 hydrochloride
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4 Cited Publications
Cat. No.: HY-101441A
CAS No.: 2320274-72-2
Purity:  98.76%
Target:  

Arenavirus

Research Areas:  

Infection

ST-193 hydrochloride is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively.
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2
KIN1408
KIN1408
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2 Cited Publications
Cat. No.: HY-19961
CAS No.: 1903800-11-2
Target:  

Flavivirus Dengue Virus RIG-I-like receptor (RLR) HCV

Research Areas:  

Infection

KIN1408 is an agonist of the RIG-1-like receptor (RLR) pathway and exhibits a broad-spectrum antiviral activity. KIN1408 exhibits activity against HCV, influenza A, dengue virus 2, Ebola, Nipah, and Lassa viruses .
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LASV-IN-1
LASV-IN-1
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Cat. No.: HY-124871
CAS No.: 554438-52-7
Purity:  99.87%
Target:  

Arenavirus

Research Areas:  

Infection

LASV-IN-1 is a Lassa fever virus (LASV) inhibitor. LASV-IN-1 binds with LASV glycoprotein (GP) and promotes virus membrane fusion and infection. LASV-IN-1 can be used for LASV infection research .
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Licoisoflavone B
Licoisoflavone B
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Cat. No.: HY-N3388
CAS No.: 66056-30-2
Category:  

Flavonoids Metabolic Disease Phenols Polyphenols 500 - Internal Server Error | MedChemExpress

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