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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
Leflunomide
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "Leflunomide" in MCE Product Catalog:
21
21 Publications Verification
Cat. No.: HY-B0083
CAS No.: 75706-12-6
Synonyms: HWA486; RS-34821; SU101
Research Areas:
Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent.
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Target:
Research Areas:
Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits pyrimidine synthesis and therefore potently decreases T cell and B cell proliferation.
Synonyms: HR325
Research Areas:
Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 µM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor .
Research Areas:
PfDHODH-IN-1 is an analogue of the active metabolite of Leflunomide. PfDHODH-IN-1 is a Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor. PfDHODH-IN-1 has antimalarial activity .
Cat. No.: HY-B0083S
CAS No.: 1189987-23-2
Target:
Research Areas:
4-(Trifluoromethyl)aniline (Standard) is the analytical standard of 4-(Trifluoromethyl)aniline. This product is intended for research and analytical applications. 4-(Trifluoromethyl) aniline (4-Aminobenzotrifluoride) is an aromatic amine and also a synthetic building block for fluorinated α-aminophosphonates. 4-(Trifluoromethyl) aniline is an impurity of Leflunomide .
Cat. No.: HY-77324S
CAS No.: 1219795-48-8
Synonyms: 4-Aminobenzotrifluoride-d4
Research Areas:
DHODH-IN-11 (Compound 14b) is a Leflunomide derivative and a weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03 .
Target:
Research Areas:
4-(Trifluoromethyl) aniline (4-Aminobenzotrifluoride) is an aromatic amine and also a synthetic building block for fluorinated α-aminophosphonates. 4-(Trifluoromethyl) aniline is an impurity of Leflunomide .
Cat. No.: HY-B0083R
CAS No.: 75706-12-6
Synonyms: HWA486 (Standard); RS-34821 (Standard); SU101 (Standard)
Category:
Cat. No.: HY-B0083S1
Synonyms: HWA486-13C6; RS-34821-13C6; SU101-13C6
Cat. No.: HY-135676
CAS No.: 1263303-93-0
Research Areas:
DHODH-IN-12 (Compound 12b) is a Leflunomide derivative and a weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07 .
Cat. No.: HY-Z8375
CAS No.: 1403564-06-6
Synonyms: Leflunomide impurity F
Target:
Research Areas:
Leflunomide impurity 1 (Leflunomide impurity F) is an impurity of Leflunomide.
Cat. No.: HY-W011669
CAS No.: 61643-23-0
Synonyms: Leflunomide 3-Isomer
Target:
Research Areas:
Leflunomide impurity 3 (Leflunomide 3-Isomer) is an impurity of Leflunomide.
Cat. No.: HY-135654
CAS No.: 183946-00-1
Research Areas:
hDHODH-IN-2 is an analogue of the active metabolite of Leflunomide. hDHODH-IN-2 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor. hDHODH-IN-1 has anti-inflammatory activity .
Cat. No.: HY-15405R
CAS No.: 163451-81-8
Synonyms: A77 1726 (Standard)
Target:
Research Areas:
Teriflunomide (Standard) is the analytical standard of Teriflunomide. This product is intended for research and analytical applications. Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits pyrimidine synthesis and therefore potently decreases T cell and B cell proliferation.
Cat. No.: HY-78861
CAS No.: 24522-30-3
Target:
Research Areas:
Leflunomide impurity 7 is an impurity of Leflunomide.
Cat. No.: HY-W010434
CAS No.: 42831-50-5
Target:
Research Areas:
Leflunomide impurity 4 is an impurity of Leflunomide.
Cat. No.: HY-Z8374
CAS No.: 208401-20-1
Target:
Research Areas:
Leflunomide impurity 5 is an impurity of Leflunomide.
Cat. No.: HY-101813R
CAS No.: 147076-36-6
Synonyms: HR325 (Standard)
Research Areas:
Laflunimus (Standard) is the analytical standard of Laflunimus. This product is intended for research and analytical applications. Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 μM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor .
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