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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Levosimendan
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Levosimendan" in MCE Product Catalog:
2
2 Cited Publications
Synonyms: Simsndan; OR-1259; (4R)-Simendan
Research Areas:
Levosimendan (Simsndan; OR-1259) is a calcium sensitiser used in the management of acutely decompensated congestive heart failure.
2
2 Cited Publications
Research Areas:
OR-1896 is an active long-lived metabolite of Levosimendan. OR-1896 is a highly selective phosphodiesterase (PDE) III isoform inhibitor and a powerful vasodilator. OR-1896 can open ATP-sensitive K + channels and has Ca 2+-sensitizing effect. OR-1896 mitigates cardiomyocyte apoptosis, cardiac remodeling and myocardial inflammation .
1
1 Cited Publications
Cat. No.: HY-W050000
CAS No.: 101328-85-2
Research Areas:
OR-1855, an active metabolite of Levosimendan (HY-14286), has effect on myometrial contractility. OR-1855 exerts anti-inflammatory effects by inhibiting IL-1β-induced ROS formation and NAD(P)H oxidase-dependent superoxide radical generation in HUVECs. OR-1855 inhibits IL-1β-induced phosphorylation p38 MAPK, ERK1/2, c-Jun and JNK in HUVECs. OR-1855 can be used for the study of inflammation .
Cat. No.: HY-14286R
CAS No.: 141505-33-1
Synonyms: Simsndan (Standard); OR-1259 (Standard); (4R)-Simendan (Standard)
Research Areas:
Levosimendan (Standard) is the analytical standard of Levosimendan. This product is intended for research and analytical applications. Levosimendan (Simsndan; OR-1259) is a calcium sensitiser used in the management of acutely decompensated congestive heart failure.
Cat. No.: HY-FL14286
CAS No.: 141505-33-1
Synonyms: Simsndan solution; OR-1259 solution
Research Areas:
Levosimendan solution is mainly composed of Levosimendan (HY-14286). Levosimendan (Simsndan; OR-1259) is a calcium sensitiser used in the management of acutely decompensated congestive heart failure.
Cat. No.: HY-W050000R
CAS No.: 101328-85-2
Research Areas:
OR-1855 (Standard) is an analytical standard of OR-1855 (HY-W050000). This product is intended for research and analytical applications. OR-1855, an active metabolite of Levosimendan (HY-14286), has effect on myometrial contractility. OR-1855 exerts anti-inflammatory effects by inhibiting IL-1β-induced ROS formation and NAD(P)H oxidase-dependent superoxide radical generation in HUVECs. OR-1855 inhibits IL-1β-induced phosphorylation p38 MAPK, ERK1/2, c-Jun and JNK in HUVECs. OR-1855 can be used for the study of inflammation .
Cat. No.: HY-W745845
CAS No.: 131741-08-7
Synonyms: (rac)-Levosimendan; (rac)-Simsndan; (rac)-OR-1259
Target:
Research Areas:
Simendan ((rac)-Levosimendan; (rac)-Simsndan; (rac)-OR-1259) is a calcium-sensitizing positive inotropic vasodilator compound that enhances myocardial contractility through calcium-dependent binding to cardiac troponin C and selectively inhibits cardiac phosphodiesterase (Phosphodiesterase) III, while inducing coronary and peripheral vasodilation and anti-ischemic effects. Simendan can be used for research on congestive heart failure, acute heart failure, myocardial infarction, myocardial ischemia, and thrombotic diseases .
Cat. No.: HY-135746S
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