227 Results for "

Linker-payload optimization

" in MedChemExpress (MCE) Product Catalog:
Products (227)

227 Results for "Linker-payload optimization" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W127512
CAS No.: 546-18-9
Target:  

Drug Intermediate

Research Areas:  

Others

5β-Cholanic acid is a hydrophobic modifier used to modify polymer carriers. 5β-Cholanic acid can improve the acid stability, cell penetration efficiency and drug sustained release ability of nanocarriers, and optimize the oral effectiveness of delivered molecules. 5β-Cholanic acid can covalently bind to Glycol chitosan (GC) to form a GC-CA conjugate, which optimizes the hydrophobic anchoring ability of nanoparticles and enables them to be stably adsorbed on the surface of PLGA nanoparticles. Such nanoparticles can resist dissociation in the gastric acid environment and maintain positive charge to enhance endocytic uptake by intestinal epithelial cells (such as Caco-2 cells). 5β-Cholanic acid can be used in the development of drug delivery systems .
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1
1 Cited Publications
Cat. No.: HY-145605
CAS No.: 1800188-47-9
Purity:  99.74%
Synonyms: HSG4112
Vutiglabridin (HSG4112), a racemic compound, is a potent anti-obesity agent . Vutiglabridin, an optimized structural analog of Glabridin, markedly supersedes Glabridin in weight reduction efficacy and chemical stability .
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1
1 Cited Publications
Cat. No.: HY-15975
CAS No.: 1261114-01-5
Target:  

Parasite

Research Areas:  

Infection

GNF179 is an optimized 8,8-dimethyl imidazolopiperazine analog that exhibits antimalarial potency (IC50 of 4.8 nM against the multidrug resistant strain W2). GNF179 is orally active .
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1
1 Cited Publications
Cat. No.: HY-154915
CAS No.: 2873452-49-2
Purity:  99.04%
MC-EVCit-PAB-MMAE (Linker-Payload 11) is a drug-linker conjugates for ADC. MC-EVCit-PAB-MMAE contains the ADCs linker (MC-EVCit-PAB) and a potent tubulin polymerization inhibitor MMAE (HY-15162) .
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1
1 Cited Publications
Cat. No.: HY-153082
Target:  

Fluorescent Dye

Research Areas:  

Others

Firefly Luciferase circRNA will express a luciferase protein, originally isolated from the Photinus pyralis (Firefly). Firefly Luciferase circRNA is ideal for monitoring and optimizing transfection efficiency and is recommended as a positive control for circular RNA transfections.
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1
1 Cited Publications
Cat. No.: HY-K0607

MCE Modified Safranin O–Fast Green Cartilage Staining Kit through an optimized staining system, cartilage matrix and bone tissue in histological sections can be clearly distinguished. This method provides high staining contrast, good sensitivity, simple operation, and good reproducibility, and is widely used for cartilage morphology observation, studies of cartilage injury and degeneration, osteochondral tissue development research, and related histological analyses.

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1
1 Cited Publications
Cat. No.: HY-K0524

MCE 2-Color Tracking SYBR qPCR Master Mix (Universal) is a 2× concentration premixed reagent utilizing a special performance-enhanced Taq DNA polymerase protected via a hot-start activation technique, and optimized qPCR buffer system to perform SYBR Green I based quantitative PCR (qPCR). The 500 rxns is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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1
1 Cited Publications
Cat. No.: HY-N1964
CAS No.: 77-06-5
Synonyms: Gibberellin A3
Category:  

Rutaceae Extract Microorganisms Gibberellins Other Diseases Plants Phytohormone Disease Research Fields 500 - Internal Server Error | MedChemExpress

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