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36 Results for "

Lp-PLA2

" in MedChemExpress (MCE) Product Catalog:

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Darapladib

8 Cited Publications

Cat. No.: HY-10521

CAS No.: 356057-34-6

Purity: 99.94%

Synonyms: SB-480848

Target:

Phospholipase Apoptosis

Research Areas:

Cardiovascular Disease Cancer

Darapladib (SB-480848) is an orally active, selective and reversible Lp-PLA2 inhibitor (IC₅₀=0.25 nM). Darapladib can trigger irreversible actions on glioma cell apoptosis and induce cycle arrest. Darapladib can be used in the study of atherosclerosis and cancer ^[2] .

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Rilapladib

3 Cited Publications

Cat. No.: HY-102004

CAS No.: 412950-08-4

Purity: 99.44%

Synonyms: SB 659032

Target:

Phospholipase

Research Areas:

Neurological Disease Inflammation/Immunology

Rilapladib (SB 659032) is a selective Lp-PLA₂ (lipoprotein-associated phospholipase A₂) inhibitor with an IC₅₀ of 230 pM . Rilapladib (SB 659032) is also a PAFR (Platelet Activating Factor Receptor) antagonist ^[2].

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