531 Results for "

MCF7 cells

" in MedChemExpress (MCE) Product Catalog:
Products (531)

531 Results for "MCF7 cells" in MCE Product Catalog:

149
Fulvestrant
Fulvestrant
0 Images
149 Publications Verification
Cat. No.: HY-13636
CAS No.: 129453-61-8
Purity:  99.92%
Synonyms: ICI 182780; ZD 9238; ZM 182780
Target:  

Estrogen Receptor/ERR Autophagy Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy .
loading...
    loading...
View All Sizes
14
CTB
CTB
0 Images
14 Cited Publications
Cat. No.: HY-134964
CAS No.: 451491-47-7
Purity:  99.93%
Target:  

Histone Acetyltransferase Apoptosis

Research Areas:  

Neurological Disease Cancer

CTB is a potent p300 histone acetyltransferase activator . CTB can effectively induce apoptosis in MCF-7 cells .
loading...
    loading...
View All Sizes
14
PX-12
PX-12
0 Images
14 Cited Publications
Cat. No.: HY-13734
CAS No.: 141400-58-0
Purity:  99.87%
Synonyms: IV-2
Target:  

Apoptosis

Research Areas:  

Cancer

PX-12(IV-2) is an irreversible inhibitor of Thioredoxin-1 (Trx-1); inhibits the growth of MCF-7 and HT-29 cells with IC50 values of 1.9 and 2.9 μM, respectively.
loading...
    loading...
View All Sizes
8
FDI-6
FDI-6
0 Images
8 Cited Publications
Cat. No.: HY-112721
CAS No.: 313380-27-7
Purity:  99.65%
Target:  

FOXM1 DNA/RNA Synthesis

Research Areas:  

Cancer

FDI-6 is an inhibitor of FOXM1. FDI-6 binds directly to FOXM1 protein, to displace FOXM1 from genomic targets in MCF-7 breast cancer cells, and induce concomitant transcriptional down-regulation.
loading...
    loading...
View All Sizes
6
Lomeguatrib
Lomeguatrib
0 Images
6 Cited Publications
Cat. No.: HY-13668
CAS No.: 192441-08-0
Purity:  98.83%
Synonyms: PaTrin-2
Target:  

DNA Methyltransferase

Research Areas:  

Cancer

Lomeguatrib is a O 6-methylguanine-DNA methyltransferase (MGMT) inhibitor, with IC50s of 9 nM in cell-free assay and ～6?nM in MCF-7 cells.
loading...
    loading...
View All Sizes
4
Danazol
Danazol
0 Images
4 Cited Publications
Cat. No.: HY-B1029
CAS No.: 17230-88-5
Target:  

PKC Apoptosis Tyrosinase

Research Areas:  

Endocrinology Cancer

Danazol inhibits the proliferation of cancer cell MDA-MB-231 and MCF-7 with IC50 of 65 µg/mL and 31 µg/mL. Danazol arrests the cell cycle at G1 phase, induces apoptosis in MDA-MB-231 through PKCα signaling pathway .
loading...
    loading...
View All Sizes
3
trans-Chalcone
trans-Chalcone
0 Images
3 Cited Publications
Cat. No.: HY-Y0598
CAS No.: 614-47-1
Synonyms: Benzylideneacetophenone
Category:  

Flavonoids 500 - Internal Server Error | MedChemExpress

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.